4. Soft Tissue Changes Flashcards

1
Q

What is the most common infection involving oral tissues in older adults

A

fungal infections

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2
Q

Two common diseases caused by fungal infections are

A

-denture stomatitis and angular chelitis

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3
Q

Other names for fungal infections

A
  • Moniliasis
  • Thrush
  • Perleche
  • Candidiasis
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4
Q

Why are fungal infections so common in the elderly

A

0Diminished immune function

  • Increased use of antibiotics
  • Change in pH and moisture levels
  • Less good OH
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5
Q

What are the four different types of candida infections -

A
  • Chronic (follows footprint of a denture)
  • Atrophic (median rhomboid glossitis- erythematous)
  • Pseudomembranous (thrush- creamy white plaques)
  • Hyperplastic (candidal leukoplakia)
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6
Q

Fungal infections are what type of infection

A

opportunistic

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7
Q

What conditions favor the growth of an opportunistic organisms

A
  • Antibiotics
  • Immunosuppressive agents
  • Cytotoxic meds
  • Corticosteroids
  • Diabetes
  • HIV/AIDS
  • Immune defects in cell-mediated immunity
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8
Q

Main things that lead to angular chelitis are

A

0Decreased vertical dimension (increases moisture accumulation)

  • Vitamin B deficiency
  • Steroid use (i.e inhalers)
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9
Q

What is unique about hyperplastic candidiasis clinically

A

will not wipe off.

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10
Q

What are the two variations of hyperplastic candida

A
  • Plaque type candida

- Chronic Nodular Candida

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11
Q

Denture stomatitis is also called

A

papillary hyperplasia

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12
Q

Describe the difference between types I, II, and III denture stomatitis

A
I= Localized minor erythematous sites
II= Major areas under denture 
III= Granular mucosa
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13
Q

List the different anti-fungal agents to manage candida

A
  • Amphotericin B
  • Nystatin
  • Clotrimazole
  • Ketokonazole
  • Fluconazole
  • Itraconazole
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14
Q

Amphotericin B comes in what forms

A
  • Oral rinse

- Pastilles (troche)

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15
Q

Nystatin comes in what forms

A
  • Oral rinse
  • Pastilles (troche)
  • Cream
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16
Q

Clotrimazole comes in what forms

A
  • Oral rinse
  • Pastilles (troche)
  • Cream
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17
Q

What are the oral systemic drugs that combat candida

A

ketokonazole

fluconazole and Itraconazole

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18
Q

Caution anti-fungal use with what other types of meds and why

A

anti-arrhytmia drugs that prolong the QT interval

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19
Q

Shingles is the result of the reactivation of the _ virus

A

herpes zoster

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20
Q

Shingles (increases/decreases) with age

A

increases

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21
Q

Delayed treatment of shingles can lead to which can persist for how long

A

post herpetic neuralgia… months to years

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22
Q

T/F more than half the people with shingles >60 get post herpetic neuralgia

A

t

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23
Q

Involvement of the external auditory canal with shingles is called

A

Ramsay Hunt syndrome

24
Q

What percent of patients with leukoplakia show dysplasia, CA in situ or invasive carcinoma

A

10-20%

25
Q

What leukoplakia characteristics make you more suspicious of cancer

A
  • large size
  • Erythroplakia
  • Varucous or ulcerative
26
Q

Most common site of metastatic cancer is in mouth

A

mandible

27
Q

T/F Oral manifestation of metastatic cancers are common

A

f-rare

28
Q

Most common carcinoma metastases are

A

breast, prostate, lung, thyroid and kidney

29
Q

Cause of papillary hyperplasia

A

unknown- thought to be caused by negative pressure on tissues (from denture or tongue in high palatal arch)

30
Q

T/F Papillary hyperplasia is only seen in denture wearers

A

f

31
Q

Treatment of appillary hyperplasia

A

reline or surgery with loop electrosurgery

32
Q

Another name for epulus fissuratum is

A

fibrous hyperplasia

33
Q

epulus fissuratum is caused by

A

chronic irritation

  • **Overextended denture flanges
  • Overextension may develop as the ridge changes
34
Q

Treatment for epulus fissuratum is

A

Surgical removal of epulus

Replace the denture

35
Q

The most common vesiculo-ulcerative diseases of the oral mucosa in elderly are

A
  • Lichen planus
  • Cicatricial (mucus membrane) pemphigoid
  • Pemphigous vulgaris
36
Q

What are the least common vesiculo-ulcerative diseases in elderly of the oral mucosa

A
  • erythema multiforme

- chronic ulcerative stomatitis

37
Q

Two types of lichen planus are

A
  • Reticular

- Erosive

38
Q

Lichen planus may be seen in assoc. with what other diseases

A
  • Liver disease

- Diabetes

39
Q

Erosive lichen planus is characterized by

A

ulceration and mucosal atrophy

Reticular areas at the periphery of the leison

40
Q

What is needed to destinguish lichen planus from pemphigodi

A

-immunoflurescent

41
Q

Treatment for lichen planus

A
  • Asymptomatic reticular= NO TX

- Erosive= corticosteroids, tecrolimus

42
Q

Cicatricial pemphiogid is more common in (men/women)

A

women

43
Q

Cause of MMP

A

autoantibodies to basement membrane components

44
Q

MMP may involve what other structures

A
  • Conjunctiva

- nasal mucosa

45
Q

Another name of MMP

A

desquamative gingivitis

46
Q

Treatment of MMP

A

Hard to treat

  • Topical steroids
  • Systemic Dapsone
47
Q

MMP has positive Nikolsky’s sign which means

A

separation of epithelium from BM (blow air on the tissue –>separation)

48
Q

Main difference between LP MMP and PV is

A

location of the immune reaction

49
Q

Location of the immune reaction of PV

A

between the epithelial cells (not the BM!!)

50
Q

Clinical presentation of PV

A

multiple ulcers

51
Q

Burning mouth syndrome is most commonly seen in what population

A

post-menopausal women

52
Q

Other names for burning mouth syndrome

A

glossopyrosis, glossodynia and burning tongue syndrome

53
Q

Typical presentation of burning mouth syndrome

A
  • No visible oral lesions
  • burning sensation
  • Often anterior tongue and anterior palate, lips
54
Q

Onset of burning mouth syndrome often follows

A

stressful event

55
Q

Things the help burning mouth syndrome

A
  • May use meds for neurogenic pain
  • Avoid spicy foods
  • Stop smoking
  • Lidocaine viscous
56
Q

Causes of burning mouth may be

A

-Xerostomia
-Anemia
-Andida
-Allergic stomatitis
-Migratory glossitis
ETC