3. Oral Changes Flashcards
Main feature of aging in cells
- Gradual cell loss
- Reduced mitotic activity
Physiologic systems most affected by aging are those containing post-mitotic cells which are what organs
- Heart
- Brain
- Muscle
- Skeletal system (less so than the other three)
When does the thymus begin to atrophy
Sexual maturity
entire thymus is involuted at what age
40
Lymphoid tissues (other than the thymus) reach max size at
puberty
Function of immune system (increases/decreases) with age
decreases (reduced number of t cells)
People with autoimmune diseases will (improve/decline) with age and why
improve because increase in auto anti-isotypic antibodies are present which fight off autoantibodies
B cell numbers (increases/decreases) with age
either stays same or increases
Primary immune system (increases/decreases) with age
decreases (inital response to antigen)
Secondary immune response (increases/decreases) with age
no change (may explain why few childhood diseases afflict the elderly
Rate of attrition in dentition is dependent on
diet and habits (not age)
Cause of higher incidence in abfraction in elderly is
unknown
Longitudinal cracks in enamel are caused by
thought to be caused by age related change in water content
Reasons why teeth are darker in color for elderly
- Thinning of enamel
- Increased optical density of dentin due to secondary dentin
- Secondary dentin considered reactive and no intrinsic aging
- Shrinkage of pulp
Hydration status of teeth (increases/decreases) with age
decreases
Dentin becomes more (flexible/brittle) with age
brittle
Reason dentin is more brittle with age
may be due to closure of tubules by crystal sedimentation
Sclerosed dentin is (more/less) translucent than normal dentin
more 9contrary to secondary dentin)
Reason for increased translucency of sclerotic dentin is
reduced refractory index difference between peri and intratubular dentin
Translucency of sclerotic dentin begins where
at the apex