4 Levels Of Protein Structure Flashcards
What are the four levels of protein structure?
Primary structure, secondary structure, tertiary structure, and quaternary structure
Individual protein molecules have up to four levels of structure
What does primary structure describe?
The linear sequence of amino acid residues in a protein
Primary structure describes the linear sequence of amino acid residues in a protein
What does secondary structure refer to?
Regularities in local conformations maintained by hydrogen bonds between amide hydrogens and carbonyl oxygens of the peptide backbone
Secondary structure refers to regularities in local conformations maintained by hydrogen bonds between amide hydrogens and carbonyl oxygens of the peptide backbone
What are the major secondary structures?
a helices, B strands, and turns
The major secondary structures are a helices, B strands, and turns
What does tertiary structure describe?
The completely folded and compacted polypeptide chain
Tertiary structure describes the completely folded and compacted polypeptide chain
What are tertiary structures stabilized by?
The interactions of amino acid side chains in non-neighboring regions of the polypeptide chain
Tertiary structures are stabilized by the interactions of amino acid side chains in non-neighboring regions of the polypeptide chain
What are distinct globular units linked by a short stretch of amino acid residues called?
Domains
Many folded polypeptides consist of several distinct globular units linked by a short stretch of amino acid residues, which are called domains
What does quaternary structure refer to?
The arrangement of two or more polypeptide chains into a multisubunit molecule
Quaternary structure refers to the arrangement of two or more polypeptide chains into a multisubunit molecule