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KFTA - Patofysiologi > [4] KFTA - "Trombose og Hæmostase" > Flashcards

[4] KFTA - "Trombose og Hæmostase" Flashcards

1
Q

Clot

A

“God” blodprop - stopper blødning

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2
Q

Thrombus

A

“Dårlig” blodprop - okkluderer kar

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3
Q

Trombocytfunktionshæmmer

A

Hæmmer dannelsen af blodpropper primært bestående af tromboytter

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4
Q

Antikoagulantia

A

Hæmmer dannelsen af blodpropper primært bestående af fibrin (samt erythrocytter)

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5
Q

Antitrombotika

A

Lægemidler der hæmmer hæmostasen

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6
Q

Hæmostase

A

Fællesbetegnelsen for de processer i kroppen som permanent kan stoppe en indre eller ydre blødning som følge af en skade på en blodåre

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7
Q

Hæmostasens funktion

A

At sikre optimalt blodflow til organer og respondere til forstyrrelser i blodet og genoprette normale tilstande

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8
Q

Hæmostasens mekanismer

A

1) Vaskulære endotel og intima
2) Blodplader
3) Komponenter i koagulationssystemet
4) Det fibrinolytiske system

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9
Q

Heparinsulfats mekanisme

A

Direkte antikoagulerende

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10
Q

Trombomodulins funktion

A

Overflade bindingssite for trombin

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11
Q

Det vaskulære endotel + intimas funktion i forhold til blodpropdannelse

A

Modvirker blodpropdannelse (clotting) med dets ladning (charge)

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12
Q

Cellen som trombocytter dannes fra?

A

Myeloide megakaryocytter

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13
Q

Trombocyt-adhæsion

A

Når trombocytter binder til karvæggen

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14
Q

Trombocyt-aggregation

A

Når trombocytter binder til andre trombocytter

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15
Q

Trombocyttens form i inaktiv tilstand

A

Bi-konveks

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16
Q

Trombocyttens form i aktiv tilstand

A

Membranprojektioner på overfladen

17
Q

Koagulationsfaktorernes dannelsessted

A

Leveren

18
Q

“a”‘ets betydning i forhold til koagulationsfaktorer (fx faktor Xa)

A

Aktiveret koagulationsfaktor

19
Q

Det fibrinolytiske systems formål

A

Modvirke eksessiv blodpropdannelse

20
Q

Plasmins rolle i det fibrinolytiske system

A

Nedbryder fibrin/fibrinogen til splitprodukter, heruder D-dimer

KFTA - Patofysiologi (10 decks)

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