4 Global health policy responses to the noncommunicable disease pandemic Flashcards
Overview Summary
This session provides a broad introduction to the topic of noncommunicable diseases (NCDs). NCDs contribute significantly to the global burden of death and disease worldwide – four sets of NCDs are estimated to have caused 74.5% of all global deaths in 2019. NCDs are a growing concern in both the Global North and South, affecting men and women in rich and poor countries alike. A set of risk factors has been identified as contributing to the majority of NCDs morbidity. In low- and middle-income countries there is a vicious cycle between NCDs and poverty, marginalisation, discrimination, which further contributes to morbidity and mortality. A strong connection has been established between economic growth and controlling NCDs. Finding solutions for curbing the global NCD pandemic, some argue, is a political, not a technical problem. The session will briefly discuss global policy efforts to address the NCD pandemic and will use the case of global tobacco control as a case-study of attempted NCD control.
Overview Aims
The aim of the session is to introduce the topic of noncommunicable disease control in global health policy and politics, which includes a discussion of the challenges faced by global governance in this field.
Overview Learning Outcomes
By the end of this session you should be able to: Define noncommunicable diseases and identify their associated risk factors; Discuss the impact of globalisation on the spread of noncommunicable diseases; Outline and evaluate existing global health policy and current policy recommendations aimed at addressing the noncommunicable disease pandemic; and Describe and evaluate the global tobacco control regime.
Key terms Non-communicable diseases (NCDs):
noncommunicable or chronic diseases are the leading cause of death globally and one of the major challenges of the 21st century (WHO 2018a: 10). NCDs are difficult to define, as all terms used – noncommunicable, chronic, lifestyle diseases - are a misnomer in one way or another (WHO 2011: 35; Allen and Feigl 2017). Broadly speaking these are diseases of long duration, generally slow progression, requiring extensive and specialised healthcare that are not passed from person to person. The 4 main types of non-communicable diseases are cardiovascular diseases (e.g. heart attack, stroke), cancers, chronic respiratory diseases (e.g. chronic obstructive pulmonary disease, asthma) and diabetes.
Key terms Modifiable risk factors
four modifiable risk factors have been identified as contributing to global NCD morbidity and mortality – tobacco use, excessive use of alcohol, diet and physical activity. These are referred to as ‘modifiable’, because they can be changed or modified by encouraging changes in individual choices and preferences
Key terms Economic globalisation
the intensification of economic activity that crosses national borders – e.g. production, consumption and the movement of people, goods, capital, services – and the growing interdependence of national economies. This process is facilitated by the increased speed and decreased cost of transport and communications.
Key terms Framework convention
a specific type of international legal instrument, which sets out broad commitments agreed by the parties, while leaving the setting of specific targets and policies either to individual states or to subsequent agreements by the parties. A framework convention is legally binding on the parties, as much as any international treaty.
- Introduction
Noncommunicable diseases (NCDs) are the ‘leading cause of death globally and one of the major challenges of the 21st century’ (WHO 2018a: 10). It is estimated that over 70% of all deaths globally are attributable to four groups of diseases – cardio-vascular diseases, cancer, respiratory diseases and diabetes (The Lancet 2018; WHO 2018b; Horton 2019). Populations of low- and middle-income countries (LMICs), as well as socioeconomically deprived groups in high-income countries, are at higher risk of developing NCDs and with nearly two-thirds of deaths occurring in LMICs being caused by NCDs, these populations are disproportionately affected by NCDs (Horton 2005; Di Cesare 2013; UNDP 2013: 11-12; WHO 2018b). The risk of dying prematurely from NCDs in a LMIC is almost double that in high-income countries (HICs) (WHO 2018b: 7). Practices associated with the prevention, control and care of NCDs are uneven and inconsistent globally, but particularly insufficient in the same regions and social strata that are most affected by and most vulnerable to these diseases.
- Introduction
The problem of NCDs has often taken the back seat in global health politics, because priority attention and funding has gone to infectious diseases, as they tend to pose an immediate risk and can more easily be framed as a security threat. There is therefore a paradox between the high morbidity and mortality caused by NCDs and the political attention and funding that they receive.
- Introduction
While four modifiable risk factors for the reduction of the incidence and prevalence of NCDs have been identified – tobacco use, harmful use of alcohol, diet and physical activity (WHO 2013), meaningful change and progress towards meeting global commitments to curbing the NCD pandemic is yet to be achieved. There is a multitude of reasons for this, which are proving complex and difficult to address or resolve. This session will discuss the scope of the NCD pandemic and consider the political economy of NCDs, thus considering the economic, social, political and legal context within which global health policy on NCDs is made and implemented. Economic factors, considered to affect NCD policies include global trade, free market economy, poverty, inequality and underdevelopment. Social debates often revolve around questions such as whether NCD prevention is an individual responsibility and can therefore be addressed through behaviour-focused policies or whether there are structural causes and determinants of NCDs, or indeed both and what a policy to address these might look like. Political discussion of NCDs focus on questions of power and global governance, with considerations of the power of multinational corporations (MNCs) in relation to that of sovereign states, the power of public-private partnerships, the architecture of global governance for health, questions around leadership, etc. The legal context is an important factor in finding solutions to the global pandemic - the problem of NCDs exists in a much broader and complex international and national legal and normative context, which shapes the possibilities of legal regulation of aspects of NCD prevention and care.
- Introduction
The session will then conclude with a discussion of the Framework Convention on Tobacco Control as a case study of the politics of NCDs and briefly discuss it in comparison to other global approaches to NCDs.
- Scope of Noncommunicable disease pandemic
This section will discuss the noncommunicable diseases (NCDs) in focus in current global discussions and policy-making efforts. It will also briefly discuss the identified risk factors and highlight the debates around these – namely, while the factors are not disputed, some believe that these factors put too much responsibility on individuals, while discounting structural factors, the role of corporate interests and activity worldwide, in seeking solutions to the NCD pandemic.
2.1 Noncommunicable disease groups
Noncommunicable diseases appear under different names – chronic diseases, lifestyle diseases, noncommunicable diseases. Neither of these terms is particularly accurate and/or effective, some argue (Allen and Feigl 2017). ‘Chronic’ refers to important shared features – these are diseases of long duration and an epidemic that takes a long time to become fully established; they require a long term systematic approach to treatment; health services must integrate their response to these diseases with responses to acute, infectious diseases (WHO 2005: 35). The issue with this is that some infectious diseases – such as HIV/AIDS can also be defined as chronic in view of the need for lifelong treatment. The term ‘noncommunicable’ sets these diseases in opposition to infectious or ‘communicable’ diseases – the term is not entirely accurate, as some cancers are caused by viruses. ‘Lifestyle-diseases’ is a term sometimes used to describe the contribution of behaviour to the onset of NCDs, but there is significant evidence about the influence of environmental factors, while ‘life-style’ choices may also be contributing factors to communicable diseases (WHO 2005: 35). Currently, the most widely used term is noncommunicable diseases (NCDs), which does not take away from the characteristics as referred to in other terms.
2.1 Noncommunicable disease groups
The leading non-communicable disease groups - cardiovascular diseases, cancers, chronic respiratory diseases and diabetes – are to a large degree caused by modifiable risk factors - tobacco, alcohol, poor nutrition, and physical inactivity; but also, by non-modifiable risk factors – e.g. age and heredity, environmental factors.
2.1 Noncommunicable disease groups Cardiovascular diseases
A group of disorders of the heart and blood vessels including: heart attacks (coronary heart disease), stroke (cerebrovascular disease), raised blood pressure (hypertension), peripheral arterial disease (affects blood vessels supplying arms and legs), blood clots (deep vein thrombosis and pulmonary embolism) and others including peripheral artery disease, rheumatic heart disease and congenital heart disease. CVDs are the leading cause of death globally – more people die of CVDs around the world than from any other cause (WHO 2017). An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Of these deaths, 85% were due to heart attack and stroke. Over three quarters of CVD deaths took place in low- and middle- income countries (WHO, 2021a).
2.1 Noncommunicable disease groups Cardiovascular diseases
The most important behavioural risk factors for heart disease and stroke are unhealthy diets, physical inactivity and tobacco use. Behavioural risk factors are responsible for about 80% of coronary heart disease and cerebrovascular disease. Harmful alcohol consumption causes at least 3.3 million deaths every year, this represents 5.9% of all deaths. Obesity and overweight (BMI < 25 is overweight, a BMI< 30 is obesity): In 2014, more than 1.9 billion adults (<18 y) were overweight.
2.1 Noncommunicable disease groups Cancer
As the WHO sets out ‘cancer is a generic term for a large group of diseases, characterised by the growth of abnormal cells beyond their usual boundaries that can then invade adjoining parts of the body and/or spread to other organs’ (WHO 2021b). Cancer can affect almost any part of the body. Cancer is estimated to be the second leading cause of death globally, estimated to have caused nearly 10 million deaths in 2020 (WHO 2021b). Approximately 70% of deaths from cancer occur in LMICs (WHO 2018c).
2.1 Noncommunicable disease groups Cancer
Risk factors for cancer include harmful levels of alcohol consumption, which can lead to risk for cancer of: oesophagus, colorectum, breast, endometrium, and kidney; use of tobacco products, which increases the risk of lung and breast cancer; unhealthy diets high in saturated fats, sugar, salt; inactivity and obesity, which can lead to increased risk for cancer of: oral cavity, pharynx, larynx, oesophagus, liver, colorectum and breast; and others. Non-modifiable risk factors for cancer include chronic infections (hepatitis B and C virus and some types of Human Papilloma Virus); environmental pollution (air, water and soil containing carcinogenic chemicals, which account for 1–4% of all cancers); occupational exposure to carcinogens (asbestos-related mesothelioma is a key example); and radiation (residential exposure to radon gas from soil and building materials accounts for between 3% and 14% of all lung cancers).
2.1 Noncommunicable disease groups Respiratory diseases
The most significant chronic respiratory diseases according to the Global Alliance against Chronic Respiratory Diseases are: Asthma (262 million people suffered from asthma in 2019, leading to 461,000 deaths); Chronic obstructive pulmonary disease (COPD – 90% of COPD deaths occur in LMICs); Respiratory allergies; Bronchiectasis; Obstructive sleep apnoea syndrome; and Pulmonary hypertension.
2.1 Noncommunicable disease groups Respiratory diseases
The most important modifiable risk factor for preventable chronic respiratory diseases is tobacco smoking, which includes second-hand tobacco smoke exposure. Non-modifiable risk factors include - indoor cooking and heating using biomass fuels such as wood, animal dung and crop residues (this practice is common in rural India and many other Asian countries); outdoor air pollution and allergens; occupational risks.
2.1 Noncommunicable disease groups Diabetes
Diabetes is a ‘chronic metabolic disease, characterised by elevated levels of blood glucose, which leads over time to severe damage to the heart, blood vessels, eyes, kidneys and nerves’ (WHO 2018d). Around 422 million people around the world have diabetes, with diabetes prevalence raising more rapidly in LMICs (WHO 2018d). Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin by itself (WHO, 2021c). Type 2 Diabetes (non-insulin-dependent) accounts for 90% of all global diabetes cases. Diabetes is primarily caused by diet, obesity, and lack of exercise; tobacco use can contribute to the onset of diabetes. More than 80% of diabetes deaths occur in low- and middle-income countries. Diabetes increases risk of other diseases. – such as heart disease and stroke, neuropathy, kidney failure. The extent of medical care for individuals with diabetes is three to four times larger than the care required by people who do not have the disease, putting a significant burden on health systems worldwide. In 2016 the WHO produced the Global Report on Diabetes discussing the extensive spread of the disease and calling governments to action to step up efforts to prevent and treat diabetes more effectively.
2.2 Modifiable behavioural risk factors
The modifiable risk factors as listed above include tobacco use, excessive alcohol consumption, unhealthy diets – associated with the consumption of saturated and trans fats, sugar and salt, insufficient physical activity. We saw that each of these factors is associated with at least two and often more of the four groups of noncommunicable diseases. In other words, controlling risk factors and changing individual choices and behaviour would have multiple benefits. These risk factors have often been referred to also as behavioural risk factors, because they are associated with particular individual behaviour and modifiable choices.
2.2 Modifiable behavioural risk factors
Governments and non-governmental actors have committed to a series of efforts to prevent NCDs through actions to affect modifiable risk factors. This commitment is illustrated by global strategies and action plans, agreed at the UN and WHO, starting with the Global Strategy for the Prevention of Noncommunicable Diseases in 2000. The most significant and committed global effort in this respect is the creation of the Framework Convention on Tobacco Control, which is a legally binding international agreement that will be discussed later in this session. Governments also take national level action by introducing national legislation, strategies, and action plans. National level action often revolves around programmes to encourage physical activity, regulate salt, and sugar intake, create and enforce legislation to ban smoking in public places, etc.
2.3 Nonmodifiable risk factors
Contributory factors to the rising prevalence of NCDs include living conditions and lifestyles and their influence on health and quality of life. Poverty, the uneven distribution of wealth (inequality), lack of education, rapid urbanization, globalisation, population aging, the general policy environment are sometimes referred to as underlying determinants (or causes of the causes) (WHO 2005: 51). Noncommunicable diseases are both a cause and a consequence of poverty and marginalisation (Hosseinpoor et al 2012a and 2012b; DiCesare et al 2013: 593; UNDP 2013). NCDs are also considered a barrier and/or a major challenge to development (UNGA 2012: 1; Reubi et al 2016: 179-180). Beaglehole and Yach (2003) argued that globalization is an important determinant of the noncommunicable disease epidemic.
2.3 Nonmodifiable risk factors
Global trade liberalisation rules and agreements, and the freedom and power that corporations must seek the least regulated politico-economic spaces to produce and trade tobacco and alcohol products, and the capacity that such corporations have to resist development country efforts to hold them accountable, illustrate some of the ways in which globalization affects NCD incidence and prevalence (Tangcharoensathien et al 2017: 359-360). This theme will be discussed in a later section. Globalisation with its ‘free movement of capital, technology, goods and services, has [had] a significant effect on lifestyles’ in LMICs and HICs alike (Wagner and Brath 2012: s40). The increases in morbidity and mortality associated with NCDs also has a significant impact on economy, with estimated losses in national income from leading NCDs ranging from 3 to 18 billion in 2005 in countries such as Brazil, India, China, the Russian Federation (Wagner and Brath 2012: s39). The feedback therefore between economic causes and consequences of NCDs is prominent, particularly so in LMICs.
Actvity 1 Research your country’s approach to curbing NCDs – this could include legislation, strategies, action plans. Share your findings and a paragraph-long reflection on the scope, scale and direction of these efforts.
Post your responses in the discussion forum and comment on the reflections of at least two other students.
- Impact of Noncommunicable diseases
The impact of noncommunicable diseases is multidimensional. NCDs directly affect those suffering from them, but also their immediate family. These diseases put a strain on personal resources and on health systems, as well as on the economy. This section examines these impacts in further detail.
3.1 Morbidity and mortality
As already noted, estimates of the global burden of noncommunicable diseases vary, but a number of sources put global NCD-related mortality at around 73% of all deaths worldwide in 2017 (The Lancet 2018; WHO 2018b; Horton 2019). More than 82% of all deaths from noncommunicable diseases (cardio-vascular diseases, respiratory diseases, cancer and diabetes) are said to occur in low- and middle-income countries (LMICs). Every year, 15 million people between the age of 30 and 69 die of NCDs. These deaths are considered premature. 85% of NCD-related premature deaths occur in LMICs (WHO 2018e). Many of these deaths are preventable as they are associated with modifiable risk factors, as discussed in the previous section.
3.1 Morbidity and mortality
NCD morbidity can be characterised as being long-term and one for which a complete cure is rarely available. In most cases treatment for NCDs requires lifetime medication and frequent use of medical services. With the NCD burden of morbidity and mortality growing in LMICs and with much of medication and care being paid out of pocket, populations in these countries suffer a double economic burden – through rising healthcare costs and falling income. Furthermore, as discussed in the previous section, some NCDs more than others, are prone to complications and heightened risk of functional impairment and disability, adding to the vicious cycle between poverty and NCDs, but also contributing to underdevelopment and inequality.
3.1 Morbidity and mortality
Studies are beginning to emerge that demonstrate multimorbidity associated with NCDs, complicating this pandemic further, as in some cases nearly one third of studied NCD-sufferers develop two or more NCDs (Mini and Thankappan 2017; The Lancet 2018; Licher et al 2019). There are significant resource implications of multimorbidity - namely, complex care needs, the need to train physicians beyond one specialist area, the need for specialist technology to support patients’ self-management of multimorbidity, integrating care in new treatment centres set up for multimorbidity (The Lancet 2018: 1637). As The Lancet article concludes, multimorbidity is extremely costly to both individuals and health-care systems. These findings should add a significant impetus to global efforts to prevent and treat NCDs, because failure to take action now is likely to have serious economic, social and political implications in the not-so-distant future.
3.2 Poverty, inequities and underdevelopment
As well as a health impact, chronic diseases have an enormous socio-economic impact - particularly on the poorest communities between and within countries. The political declaration from the first UN High Level Meeting on the Prevention and Control of NCDs in 2011 noted the concern of policy-makers with the vicious cycle of poverty contributing to the rise of NCDs and the prevalence of NCDs and their risk factors worsening poverty (UNGA 2012: 4). A report from the African Union in April 2013 found that the exorbitant costs of NCDs are forcing 100 million people in Africa into poverty annually. Unless addressed the NCD crisis could cost up to USD30 trillion in treatment costs by 2030, estimated as 48% of global GDP (Kamineni 2019). Another way to look at the cost of NCDs is as a USD47 trillion in lost gross domestic product globally from 2011 to 2025 (Ghebreyesus 2018: 1973).