4. Genetics, Evolution, Development and Plasticity Flashcards

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1
Q

Suppose you have high sensitivity to the taste of PTC. If your mother also has high sensitivity, what (if anything) can you predict about your father’s taste sensitivity?

a. He has high taste sensitivity.
b. He has low taste sensitivity.
c. We do not have enough information to make a prediction.

A

c. We do not have enough information to make a prediction.

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2
Q

Suppose you have high sensitivity to the taste of PTC. If your mother has low sensitivity, what (if anything) can you predict about your father’s taste sensitivity?

a. He has high taste sensitivity.
b. He has low taste sensitivity.
c. We do not have enough information to make a prediction.

A

a. He has high taste sensitivity.

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3
Q

What is a sex-limited gene?

a. A gene on the X chromosome
b. A gene on the Y chromosome
c. A gene that sex hormones activate
d. A gene that becomes active during sexual activity

A

c. A gene that sex hormones activate

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4
Q

Suppose someone identifies a “gene for” certain aspects of sexual development. In what ways might that statement be misleading?

a. The statement didn’t specify whether the gene was dominant or recessive.
b. Many aspects of sexual development are not apparent until puberty.
c. Almost any characteristic depends on many genes, as well as influences from the environment.

A

c. Almost any characteristic depends on many genes, as well as influences from the environment.

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5
Q

How does an epigenetic change differ from a mutation?

a. An epigenetic change is a duplication or deletion of part of a gene.
b. An epigenetic change is an alteration of gene activity without structurally replacing any part of the gene itself.
c. An epigenetic change alters more than one gene at a time.
d. An epigenetic change is beneficial, whereas a mutation is harmful.

A

b. An epigenetic change is an alteration of gene activity without structurally replacing any part of the gene itself.

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6
Q

How does adding a methyl or acetyl group to a histone protein alter gene activity?

a. A methyl group turns genes off. An acetyl group loosens histone’s grip and increases gene activation.
b. A methyl group turns genes on. An acetyl group tightens histone’s grip and decreases gene activation.
c. A methyl group increases the probability of a mutation, whereas an acetyl group decreases the probability.
d. A methyl group decreases the probability of a mutation, whereas an acetyl group increases the probability.

A

a. A methyl group turns genes off. An acetyl group loosens histone’s grip and increases gene activation.

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7
Q

Which of the following is NOT one of the main types of evidence to estimate the heritability of some behavior?

a. Comparisons between monozygotic and dizygotic twins
b. Similarities between adopted children and their biological parents
c. Examination of identified genes that might vary between people showing one behavior and another
d. Comparisons of people living in different cultures

A

d. Comparisons of people living in different culture

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8
Q

Suppose someone determines the heritability of IQ scores for a given population. Then society changes in a way that provides the best possible opportunity for everyone within that population. How will the heritability of IQ change, if at all?

a. Heritability will increase.
b. Heritability will decrease.
c. Heritability will stay the same.

A

a. Heritability will increase.

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9
Q

The information about phenylketonuria (PKU) supports which of these conclusions?

a. Several genes active in the human brain are not found in other species.
b. Each brain area controls a different behavioral function.
c. A change in the environment can alter the effects of a gene.
d. Epigenetic changes depend on methyl and acetate groups.

A

c. A change in the environment can alter the effects of a gene.

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10
Q

What, if anything, can we predict about the future of human evolution?

a. People will get smarter, wiser, and more cooperative.
b. People will not change, because evolution no longer affects humans.
c. People will become more like whichever people tend to have the most children.

A

c. People will become more like whichever people tend to have the most children.

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11
Q

Which of these is the least acceptable explanation for how an altruistic gene might spread in a population?

a. Selection for a gene that benefits the individuals’ relatives
b. Selection for helping individuals who might return the favor
c. Selection for genes that benefit the species
d. Selection for groups that are more cooperative than other groups

A

c. Selection for genes that benefit the species

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12
Q

Which part of a neuron forms first, if either?

a. The axon forms first.
b. The dendrites form first.
c. They form at the same time.

A

a. The axon forms first.

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13
Q

What is unusual about the olfactory receptors?

a. Olfactory neurons have more than one axon.
b. Humans do not begin forming olfactory neurons until nearly 2 years old.
c. We continue forming new olfactory neurons throughout life.
d. An unusually strong blood–brain barrier protects olfactory neurons from damage.

A

c. We continue forming new olfactory neurons throughout life.

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14
Q

The 14C concentration in the atmosphere has been declining since 1963. The 14C concentration in neurons of a person’s cerebral cortex and olfactory bulbs corresponds to that of ___.

a. the year of the person’s birth
b. about halfway between the person’s birth and the present year
c. the year the person’s education ended
d. the current year

A

a. the year of the person’s birth

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15
Q

When Sperry cut a newt’s optic nerve and turned the eye upside down, what happened?

a. Axons of the optic nerve grew randomly and attached diffusely to target cells in the tectum.
b. Axons of the optic nerve grew back to their original targets.
c. Axons of the optic nerve grew back to targets appropriate to their new location in the eye.
d. At first the axons grew back randomly, but then they established appropriate connections by learning.

A

b. Axons of the optic nerve grew back to their original targets.

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16
Q

If axons from the retina were prevented from showing spontaneous activity during early development, what would be the probable effect on development of the thalamus?

a. Axon attachment would be more precise than usual.
b. Axons would branch more widely, establishing more connections than usual.
c. Axons would not fine-tune their adjustment based on experience, so their connections would be less precise.
d. Axons would attach in the same way as usual, unaffected by the change.

A

c. Axons would not fine-tune their adjustment based on experience, so their connections would be less precise.

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17
Q

Why does the spinal cord have the right number of axons to innervate all the muscle cells?

a. Each muscle cell sends a chemical message telling the spinal cord to make a neuron.
b. The genes cause a certain number of neurons to form and the same number of muscles to form.
c. Immature cells divide, with one daughter cell becoming a neuron and the other becoming a muscle.
d. The spinal cord makes an excess of neurons, but those that fail to innervate a muscle die.

A

d. The spinal cord makes an excess of neurons, but those that fail to innervate a muscle die.

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18
Q

What is apoptosis?

a. A chemical that damages neurons
b. A chemical that keeps neurons alive
c. A programmed mechanism of cell death
d. A machine that records neuron activity

A

c. A programmed mechanism of cell death

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19
Q

Which neurons depend on nerve growth factor to prevent apoptosis in early development?

a. Neurons in the brain
b. Neurons in the sympathetic nervous system
c. Both
d. Neither

A

b. Neurons in the sympathetic nervous system

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20
Q

At what age does a person have the largest number of neurons?

a. Before or shortly after birth
b. Equally at all times of life
c. Adolescence
d. Adulthood

A

a. Before or shortly after birth

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21
Q

If a pregnant woman drinks alcohol, alcohol harms the brain of the fetus not only while it is in the system, but also while it is washing away after drinking. What is the danger while alcohol is washing away?

a. Temperature in the brain may decrease.
b. Blood pressure in the brain may decrease.
c. Excess inhibition at GABA synapses can lead to apoptosis.
d. Overstimulation at glutamate synapses can poison the mitochondria.

A

d. Overstimulation at glutamate synapses can poison the mitochondria.

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22
Q

In the ferret study, what evidence indicated that visual input to the auditory portions of the brain actually produced a visual sensation?

a. Bright flashes of light to the rewired eye caused the ferrets to blink both eyes.
b. Recordings from individual cells of the rewired temporal cortex showed the same patterns usually seen in cells of the occipital cortex.
c. Ferrets could find their way around an unfamiliar room even with the normal eye closed.
d. Ferrets that learned to turn one way in response to light in the normal eye turned the same way to light in the rewired eye.

A

d. Ferrets that learned to turn one way in response to light in the normal eye turned the same way to light in the rewired eye.

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23
Q

An enriched environment promotes growth of axons and dendrites in laboratory rodents. What is known to be one important reason for this effect?

a. Increased physical activity
b. Increased happiness
c. Increased relaxation
d. Increased empathy with other animals

A

a. Increased physical activity

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24
Q

If a person is born blind, in what way do the senses of hearing and touch improve?

a. The person gradually develops more receptors in the ears and skin.
b. The number of receptors does not change, but each of them becomes more responsive to weak stimuli.
c. The receptors in the ears and skin send faster action potentials to the brain.
d. Through practice the person learns to increase attention to hearing and touch, and those sensations come to activate the occipital cortex.

A

d. Through practice the person learns to increase attention to hearing and touch, and those sensations come to activate the occipital cortex.

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25
Q

Of the following, which is the strongest evidence to indicate that musical training modifies brain anatomy?

a. The gray matter of several cortical areas is thicker in professional musicians than in nonmusicians.
b. A larger than average portion of the right somatosensory cortex responds to the left hand in stringed instrument players than in other people.
c. At age 6, children starting musical training did not differ from average, but 15 months later they showed enlargements of several brain areas.

A

c. At age 6, children starting musical training did not differ from average, but 15 months later they showed enlargements of several brain areas.

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26
Q

Many studies report brain changes after special experiences in adulthood, such as learning to juggle or learning to play golf. Why are some researchers skeptical of these findings?

a. The adult brain cannot change anatomically.
b. Most of the reported results were small and have not been replicated.
c. Most of the reported studies had no control group.
d. Most of the reported studies required many years of training.

A

b. Most of the reported results were small and have not been replicated.

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27
Q

What causes musician’s cramp?

a. Changes in the muscles and tendons of the hand
b. Rewiring of the cerebral cortex
c. Loss of myelin on the motor nerves to the hand
d. Changes in the touch receptors of the hand

A

b. Rewiring of the cerebral cortex

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28
Q

Is it reasonable to argue that adolescents are mature enough to make some decisions and not others?

a. No. This argument is based entirely on political leanings.
b. Perhaps. Adolescents reason in a mature way for unimportant decisions, but not for important ones.
c. Perhaps. Adolescents reason in an immature way when they decide quickly under peer pressure.
d. Perhaps. Adolescents reason in a mature way when they are happy but not when they are sad.

A

c. Perhaps. Adolescents reason in an immature way when they decide quickly under peer pressure.

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29
Q

Immaturity of the prefrontal cortex is a possible explanation for which aspect of adolescent behavior?

a. Impulsivity
b. Increased interest in social contact
c. Increased appetite
d. Sleepiness during the day

A

a. Impulsivity

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30
Q

Why do many older people continue to hold important jobs in spite of the declines in memory and brain function that are known to occur in old age?

a. Laws prevent them from being fired.
b. Although their jobs are important, they don’t require much brain activity.
c. Old people take the credit for work that younger people actually do.
d. The declines on average do not apply to all people.

A

d. The declines on average do not apply to all people.

31
Q

What are the two kinds of stroke, and what causes each kind?

a. Ischemia (blocked blood vessel) and hemorrhage (burst blood vessel)
b. Hemorrhage (blocked blood vessel) and ischemia (burst blood vessel)
c. Active (increased brain activity) and passive (decreased brain activity)
d. Hyperthermic (increased brain temperature) and hypothermic (decreased brain temperature)

A

a. Ischemia (blocked blood vessel) and hemorrhage (burst blood vessel)

32
Q

The drug ___ is helpful for strokes related to ___.

a. Xanax . . . ischemia
b. Xanax . . . hemorrhage
c. tPA . . . ischemia
d. tPA . . . hemorrhage

A

c. tPA . . . ischemia

33
Q

Name two procedures that decrease the damage caused by strokes in laboratory animals, although physicians so far have seldom tried them with people.

a. Dehydration and lithium
b. Increased blood flow and antidepressants
c. Decreased body temperature and cannabinoids
d. Increased body temperature and tranquilizers

A

c. Decreased body temperature and cannabinoids

34
Q

What is diaschisis?

a. Impaired performance of neurons because neurons that used to provide them with input have been damaged
b. Improved performance of neurons after they have received extra stimulation
c. Alternation between activation of the left hemisphere and activation of the right hemisphere
d. Sprouting of axons to provide input to cells that have lost their normal input

A

a. Impaired performance of neurons because neurons that used to provide them with input have been damaged

35
Q

After someone has had a stroke, what kind of drug might be helpful, and which brain areas should receive it?

a. It would be best to deliver tranquilizers to the damaged area of the brain.
b. It would be best to deliver stimulant drugs to the damaged area of the brain.
c. It would be best to deliver tranquilizers to cells previously connected to the neurons that have been damaged.
d. It would be best to deliver stimulant drugs to cells previously connected to the neurons that have been damaged.

A

d. It would be best to deliver stimulant drugs to cells previously connected to the neurons that have been damaged.

36
Q

Where does collateral sprouting take place?

a. In the cell body
b. In the axon
c. In the dendrites
d. In both the axons and the dendrites

A

b. In the axon

37
Q

Where does denervation supersensitivity take place?

a. In the cell body
b. In the axon
c. In the dendrites
d. In both the axons and the dendrites

A

c. In the dendrites

38
Q

What causes the phantom limb experience?

a. Irritation of receptors at the stump where the amputation occurred
b. Spontaneous activity of receptors at the stump where the amputation occurred
c. Reorganization of the sensory cortex
d. A psychiatric reaction based on denial of the amputation

A

c. Reorganization of the sensory cortex

39
Q

Suppose a patient uses only the right arm following injury that blocked all sensation from the left arm. Of the following, which is the most promising therapy?

a. Electrically stimulate the skin of the left arm
b. Tie the right arm behind the person’s back
c. Blindfold the person

A

b. Tie the right arm behind the person’s back

40
Q

Suppose you have high sensitivity to tasting PTC. If your mother can also taste it easily, what (if anything) can you predict about your father’s ability to taste it?

A

We do not have enough Information

41
Q

Suppose you have high sensitivity to the taste of PTC. If your mother has low sensitivity, what (if anything) can you predict about your father’s taste sensitivity?

A

If your mother has low sensitivity, you must have inherited your high-sensitivity gene from your father, so he must have high sensitivity.

42
Q

How does a sex-linked gene differ from a sex-limited gene?

A

A sex-linked gene is on the X or Y chromosome. A sex-limited gene is on an autosomal chromosome, but activated in one sex more than in the other.

43
Q

Suppose someone identifies a “gene for” certain aspects of sexual development. In what ways might that statement be misleading?

A

Almost any characteristic depends on more than one gene, as well as influences from the environment.

44
Q

How does an epigenetic change differ from a mutation?

A

A mutation is a permanent change in part of a chromosome. An epigenetic change is an increase or decrease in the activity of a gene or group of genes.

45
Q

How does adding a methyl or acetyl group to a histone protein alter gene activity?

A

Adding a methyl group turns genes off. An acetyl group loosens histone’s grip and increases gene activation.

46
Q

What are the main types of evidence to estimate the heritability of some behavior?

A

One type of evidence is greater similarity between monozygotic twins than dizygotic twins. Another is resemblance between adopted children and their biological parents. A third is a demonstration that a particular gene is more common than average among people who show a particular behavior.

47
Q

Suppose someone determines the heritability of IQ scores for a given population. Then society changes in a way that provides the best possible opportunity for everyone within that population. Will heritability of IQ increase, decrease, or stay the same?

A

Heritability will increase. Heritability estimates how much of the variation is due to differences in genes. If everyone has the same environment, then differences in environment cannot account for much of the remaining differences in IQ scores. Therefore, the relative role of genetic differences will be greater.

48
Q

What example illustrates the point that even if some characteristic is highly heritable, a change in the environment can alter it?

A

Keeping a child with the PKU gene on a strict low-phenylalanine diet prevents the mental retardation that the gene ordinarily causes. The general point is that sometimes a highly heritable condition can be modified environmentally.

49
Q

Many people believe the human appendix is useless. Will it become smaller and smaller with each generation?

A

No. Failure to need a structure does not make it smaller in the next generation. The appendix will shrink only if people with a gene for a smaller appendix reproduce more successfully than other people do.

50
Q

What are plausible ways for possible altruistic genes to spread in a population?

A

Altruistic genes could spread because they facilitate care for one’s kin or because they facilitate exchanges of favors with others (reciprocal altruism). Group selection may also work under some circumstances, especially if the cooperative group has some way to punish or expel an uncooperative individual.

51
Q

Which develops first, a neuron’s axon or its dendrites?

A

Axons develop first

52
Q

New receptor neurons form in adult rodents for which sensory system?

A

Olfaction

53
Q

What evidence indicated that new neurons seldom or never form in the human cerebral cortex and olfactory bulb?

A

The 14C concentration in the DNA of human neurons in the cerebral cortex and olfactory bulbs corresponds to the level during the year the person was born, indicating that all or nearly all of those neurons are as old as the person is.

54
Q

What was Sperry’s evidence that axons grow to a specific target instead of attaching at random?

A

If he cut a newt’s eye and inverted it, axons grew back to their original targets, even though the connections were inappropriate to their new positions on the eye.

55
Q

If axons from the retina were prevented from showing spontaneous activity during early development, what would be the probable effect on development of the thalamus?

A

The axons would attach based on a chemical gradient but could not fine-tune their adjustment based on experience. Therefore, the connections would be less precise.

56
Q

What process assures that the spinal cord has the right number of axons to innervate all the muscle cells?

A

The nervous system builds far more neurons than it needs and discards through apoptosis those that do not make lasting synapses.

57
Q

What class of chemicals prevents apoptosis in the sympathetic nervous system?

A

Neurotrophins, such as nerve growth factor

58
Q

At what age does a person have the greatest number of neurons—early in life, during adolescence, or during adulthood?

A

The neuron number is greatest early in life.

59
Q

In the ferret study, how did the experimenters determine that visual input to the auditory portions of the brain actually produced a visual sensation?

A

They trained the ferrets to respond to stimuli on the normal side, turning one direction in response to sounds and the other direction to lights. Then they presented light to the rewired side and saw that the ferret again turned in the direction it had associated with lights.

60
Q

An enriched environment promotes growth of axons and dendrites in laboratory rodents. What is known to be one mportant reason for this effect?

A

Animals in an enriched environment are more active, and their exercise enhances growth of axons and dendrites.

61
Q

Name two kinds of evidence indicating that touch information from the fingers activates the occipital cortex of people blind since birth.

A

First, brain scans indicate increased activity in the occipital cortex while blind people perform tasks such as feeling two objects and saying whether they are the same or different. Second, temporary inactivation of the occipital cortex blocks blind people’s ability to perform that task, without affecting the ability of sighted people.

62
Q

Which brain area shows expanded representation of the left hand in people who began practicing stringed instruments in childhood and continued for many years?

A

Somatosensory cortex (postcentral gyrus) of the right hemisphere.

63
Q

What change in the brain is responsible for musician’s cramp?

A

Extensive practice of violin, piano, or other instruments causes expanded representation of the fingers in the somatosensory cortex, as well as displacement of representation of one or more fingers in the motor cortex. If the sensory representation of two fingers overlaps too much, the person cannot feel them separately or move them separately.

64
Q

Under what circumstances are adolescents most likely to make an impulsive decision?

A

Adolescents are most likely to make an impulsive decision in the presence of peer pressure

65
Q

When people claim that adolescents make risky decisions because of a lack of inhibition, which brain area do they point to as being responsible for inhibition?

A

The prefrontal cortex

66
Q

What are the two kinds of stroke, and what causes each kind?

A

The more common form, ischemia, is the result of an occlusion of an artery. The other form, hemorrhage, is the result of a ruptured artery.

67
Q

Why is tPA not helpful in cases of hemorrhage?

A

The drug tPA breaks up blood clots, and hemorrhage results from a ruptured blood vessel, not a blood clot.

68
Q

If one of your relatives has a stroke and a well-meaning person offers a blanket, what should you do?

A

Refuse the blanket. Recovery will be best if the stroke victim remains cold.

69
Q

After someone has had a stroke, would it be best (if possible) to direct stimulant drugs to the cells that were damaged or somewhere else?

A

It is best to direct the amphetamine to the cells that had been receiving input from the damaged cells. Presumably, the loss of input has produced diaschisis.

70
Q

Is collateral sprouting a change in axons or dendritic receptors?

A

Axons

71
Q

Is denervation supersensitivity a change in axons or dendritic receptors?

A

Dendritic receptors

72
Q

What is responsible for the phantom limb experience?

A

Synapses that used to receive input from the now amputated part become vacant. Axons representing another part of the body take over those synapses. Now stimulation of this other part activates the synapses associated with the amputated area, but that stimulation feels like the amputated area.

73
Q

A monkey that loses sensation from one arm stops using it, but a monkey that loses sensation from both arms does use them. Why?

A

A monkey that lost sensation in one arm is capable of moving it, but finds it easier to walk with the three intact limbs. When both arms lose their sensations, the monkey is forced to rely on them.