(4) ECT Flashcards
Site of etc
Mitochondria
Attached to inner folded membrane (cristae) = enzymes, proteins involved in ETC & ATP synthesis
M found in metabolically active cells
Electron Transport chain ETC
H atoms // electrons carried by coenzymes NAD & FAD : to ETC
Energy within electrons is converted to ATP
ETC & ATP synthesis
H atoms produced during glycolysis & Krebs cycle; combine w/ COE NAD & FAD which are attached to cristae of Mit
Red NAD & FAD donate electrons of H to first mol in ETC
This releases protons from H atoms & protons are ATd across inner Mit membrane
Electrons pass along a chain of ETCmols in series of O-R reactions. Electrons lose energy as they pass down chain
Energy -> combines ADP + Pi to make ATP
Energy is released in form of heat
Protons accumulate in space b/w MitMembrane before diffuse back into Mit Matrix through special channel proteins
End of chain electrons combine w/ protons and O to form H20
02: final electron acceptor in etc
Importance of O as final acceptor
Oxygen = final hydrogen atoms acceptor
Without oxygen ; H ions (protons) & electrons would back up along chain
Respiration = comes to halt
Effect of cyanide
NC inhibitor for; final enzyme in ETC
Enzyme which catalyses addition Hion & Electrons to 02 to form H20
Inhibition causes H ions & electrons to accumulate on carries ; brings resp to halt