4. Breast carcinoma Flashcards
1
Q
How common is it?
A
Most common type of cancer in the UK
1 in 8 women
Rare in men
2
Q
Who does it affect?
A
Most commonly >50s but can occur in all ages
3
Q
What causes it?
A
Oestrogen stimulates hyperplasia of cells (in ducts, lobules or elsewhere)
4
Q
What risk factors are there?
A
Increasing age FH, previous breast cancer Tall, overweight / obese Previous benign lump Alcohol
5
Q
What signs may the patient have on examination?
A
Palpable lump in breast / armpit
Peau d’orange
6
Q
What other conditions might present similarly?
A
Benign lesions (cyst, fibroadenomas) Secondary breast cancer
7
Q
How would you investigate?
A
Triple assessment - mammogram and biopsy
8
Q
What treatments are there?
A
Surgery followed by radio/chemotherapy
Sometimes hormone targeted treatment
9
Q
What types are there?
A
In situ (DCIS) Invasive (triple negative, inflammatory, Paget's disease, Phyllodes tumour, angiosarcoma)
