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Stoffwechelstörungen > 4. Antidiabetika > Flashcards

4. Antidiabetika Flashcards

1
Q

(Antidiabetika)

Kontraindikationen (3)

A
  • Schwangerschaft
  • Stillzeit
  • schwere Niereninsuffizienz
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2
Q

(Antidiabetika)

Klassen (6)

A
  • Biguanidderivate
  • Sulfonylharnstoffderivate
  • Sulfonylharnstoff-Analoga
  • GLP-1-Analoga
  • SGLT-2-Inhibitoren
  • DDP-4-Inhibitoren
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3
Q

(Antidiabetika)

Mittel der Wahl

A

Biguanidderivate

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4
Q

(Antidiabetika)

Biguanidderivate: Wirkstoff

A

Metformin

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5
Q

(Antidiabetika)

Biguanidderivate: Wirkung

A

Hemmung der Glycogenolyse und Gluconeogenese in der Leber

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6
Q

(Antidiabetika)

Biguanidderivate: Nebenwirkungen (4)

A
  • Azidose
  • Dysgeusie
  • Vitamin-B-12-Mangel
  • gastrointestinale Beschwerden
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7
Q

(Antidiabetika)

Sulfonylharnstoffderivate: Wirkstoffe (3)

A
  • Glibenclamid,
  • Glimepirid
  • Gliclazid
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8
Q

(Antidiabetika)

Sulfonylharnstoffderivate: Wirkung

A

Erhöhung der Insulinfreisetzung

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9
Q

(Antidiabetika)

Sulfonylharnstoffderivate: Nebenwirkung

A

Hypoglykämie

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10
Q

(Antidiabetika)

Sulfonylharnstoff-Analoga: Klasse

A

Glinide

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11
Q

(Antidiabetika)

Sulfonylharnstoff-Analoga: Wirkstoffe (2)

A
  1. Repaglinid
  2. Nateglinid
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12
Q

(Antidiabetika)

Sulfonylharnstoff-Analoga: Wirkung

A

Erhöhung der Insulinfreisetzung

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13
Q

(Antidiabetika)

Sulfonylharnstoff-Analoga: Nebenwirkung

A

Hypoglykämie

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14
Q

(Antidiabetika)

GLP-1-Analoga: Klasse

A

Inkretinmimetika

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15
Q

(Antidiabetika)

GLP-1-Analoga: Wirkstoffe (3)

A
  • Semaglutid
  • Exenatid
  • Liraglutid
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16
Q

(Antidiabetika)

GLP-1-Analoga: Wirkungen (2)

A
  • Stimulierung der glukosevermittelten Insulinausschüttung
  • Hemmung der Glukagonfreisetzung
17
Q

(Antidiabetika)

GLP-1-Analoga: Nebenwirkung

A

gastrointestinale Beschwerden

18
Q

(Antidiabetika)

SGLT-2-Inhibitoren: Klasse

A

Gliflozine

19
Q

(Antidiabetika)

SGLT-2-Inhibitoren: Wirkstoffe (3)

A
  • Dapagliflozin
  • Empagliflozin
  • Ertugliflozin
20
Q

(Antidiabetika)

SGLT-2-Inhibitoren: Wirkung

A

Hemmung der Rückersorption der Glukose

21
Q

(Antidiabetika)

SGLT-2-Inhibitoren: Nebenwirkungen (3)

A
  • Harnwegsinfekte
  • diabetische Ketoazidose
  • Hypotonie und Hypovolämie
22
Q

(Antidiabetika)

DDP-4-Inhibitoren: Klasse

A

Gliptine

23
Q

(Antidiabetika)

DDP-4-Inhibitoren: Wirkstoffe (3)

A
  • Sitagliptin
  • Saxagliptin
  • Vildagliptin
24
Q

(Antidiabetika)

DDP-4-Inhibitoren: Wirkung

A

Verstärkung des Inkretineffekts

25
Q

(Antidiabetika)

DDP-4-Inhibitoren: Nebenwirkung

A

gastrointestinale Beschwerden

Stoffwechelstörungen (12 decks)

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