4

Question 1

3 contraindications for PGAs

Answer 1

Active inflamm (uveitis)
History of herpes simplex
CME risk (e.g. post op ct)

Question 2

List BEZPOP

Answer 2

Bepreve
Elestat
Zaditor
Patanol
Optivar
Pataday

Question 3

List MCS

Answer 3

Cromolyn sodium
Alamast
Alomide
Alocril

Question 4

CAI SEs

Answer 4

Common: metallic taste, tingling in hands/feet, metabolic acidosis

Serious: aplastic anemia, thrombocytopenia, agranulocytosis

Other: malaise, fatigue, weight loss, anorexia, impotence, depression, diarrhea, myopic shifts

Question 5

MOA of PGAs

Answer 5

First line for POAG

1) PGF2 receptors on ciliary muscle -> reduction of neighboring collagen (MMPs) -> incr uveoscleral outflow
2) skin receptors -> activ phospholipase C to alter hair follicles

Question 6

Tetracyclines SEs

Answer 6

Contraindicated in pregnancy and children
Pseudotumor cerebri/intracranial hypertension (CAATSS)
Bone growth retardation
Discoloration of teeth

Mino = blue sclera, pigmented cysts on conj

Question 7

Pseudotumor cerebri/intracranial hypertension

Answer 7

CAATSS
Contraceptives
Accutane
Vit A
Tetracycline
Synthroid
Steroids

Question 8

Indomethacin SE (2)

Answer 8

Retinal hemorrhage
Pigmentary changes (esp macula)
-mottling, whorl K

(NSAID for gout)

Question 9

Isotretinoin/Accutane SE (6)

Answer 9

Blepharoconjunctivitis
Dry eyes
Pseudotumor cerebri
Loss of color vision
Nyctalopia
Lid edema
Cataracts have been reported