4/5 revision Flashcards

1
Q

Medical treatment for BPH?

A

Alpha adrenergic receptor antagonist - tamsulosin

5 alpha reductase inhibitor - finasteride

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2
Q

Urgency incontinence medical treatment?

A

Beta-3-agonist - Mirabegron

Botox injections

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3
Q

CKD symptoms / signs

A
Restless legs
Oedema
Anaemia
Acidosis
Hypertension
Amenorrhoea / impotence
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4
Q

CKD treatment

A

Symptoms -
EPO/iron for anaemia, Gabapentin for legs, Furosemide and fluid and Na+ restriction for oedema, Sodium bicarbonate for acidosis

Haemo/peritoneal dialysis
Transplant

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5
Q

Acromegaly medical treatment

A

Dopamine agonist- cabergoline
Somatostatin analogue - pegvisomant
GH receptor antagonist

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6
Q

Investigations for Cushing’s

A
  1. Plasma cortisol - high
  2. Dexamethasone suppression - no suppression
  3. Plasma ACTH
    • Undetectable = adrenal tumour
    • Detectable –> CRH test –> rise = pit, none ectopic
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7
Q

Nephrogenic diabetes insipidus Tx

A

Treat underlying cause
Bendroflumethiazide
NSAIDs

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8
Q

Medical treatment for SiADH

A

Vasopressin receptor agonist - Tolvaptan

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9
Q

3 signs of Graves’

A

Eye disease
Thyroid acropachy
Pretibial myxoedema

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10
Q

Thyrotoxic storm symptoms / signs

A
Pyrexia
Agitation / confusion
D+V
Tachycardia + AF
Heart failure
Coma
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11
Q

Thyrotoxic storm treatment

A

Beta-blocker –> carbimazole –> dexamethasone

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12
Q

Myxoedema coma symptoms / signs

A
Confusion
Hypothermia
Hypoventilation
Hypoglycaemia
Hyponatraemia
Heart failure
Coma
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13
Q

Myxoedema coma treatment

A

IV T3 and glucose

Rewarm

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14
Q

Which antibodies are present in addisons?

A

21-hydroxylase adrenal autoantibodies

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15
Q

What is Conn’s syndrome

A

Hyperaldosteronism caused by a solitary adenoma

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16
Q

What do Chvostek and Trousseau signs show?

A

Hypocalcaemia

17
Q

Name a sulphonylurea

A

Glipizide

18
Q

Which hypoglycaemic agent is C/I in pregnancy?

A

Sulphonylurea - glipizide

19
Q

Treatment of hypokalaemia

A

oral K+ or IV K+

20
Q

Treatment of hyperkalaemia

A

polystyrene sulphonate resin

21
Q

Corrected calcium

A

total serum calcium - 0.02(40-serum albumin)

22
Q

Name 3 benign breast diseases

A

Fibroadenoma
Breast cysts
Intraductal papilloma

23
Q

Name 3 Tamoxifen S/E

A

Fatigue, weight gain, hot flushes

24
Q

Name 3 Herceptin S/E

A

Aches and pains, fatigue, diarrhoea

25
Q

SiADH causes

A

Malignancy, drugs, CNS eg.meningitis

26
Q

SiADH Tx

A

Treat underlying cause, fluid restriction, Tolvaptan - vasopressin receptor antagonist

27
Q

Hyperaldosteronism symptoms

A

Constipation, weakness, cramps, paraesthesis, polyuria/polydipsia (+hypertension)

28
Q

Hyperaldosteronism Tx

A

Conn’s - adrenalectomy
Spironolactone
Caclium gluconate + insulin