4-15-13 Flashcards

1
Q

Rate limiting enzyme for
Glycolysis
Gluconeogenesis
TCA cycle

A

Phosphofructokinase
Fructose1-6 bisphosphatase
Isocitrate dehydrogenase

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2
Q

Warfarin inhibits what enzyme?

A

Epoxide Reductase which is responsible for reclyclin vitamin K. Vitamin needed to produce clottting factor 10,9,7,2 in the liver.

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3
Q

Cannot use warfarin during preg. Use heparin.

A

.

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4
Q

Warfarin antidote

A

Vit. K levels and FFP.

Don’t eat things with vit. K while using warfarin

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5
Q

Warfarin only affect the synthesis of new clotting factor.

A

Does nothing on already circulating/made clotting factors.

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6
Q

Warfarin causes a transient hypercoagulable state.

A

Give Heparin for a couple of days with warfarin.

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7
Q

Heparin antidote?

A

Protamin Sulfate

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8
Q

How to monitor Heparin, Warfarin and Enoxaparin?

A

Heparin
Warfarin
Enoxaparin = Factor Xa activity

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