4-15-13 Flashcards
Rate limiting enzyme for
Glycolysis
Gluconeogenesis
TCA cycle
Phosphofructokinase
Fructose1-6 bisphosphatase
Isocitrate dehydrogenase
Warfarin inhibits what enzyme?
Epoxide Reductase which is responsible for reclyclin vitamin K. Vitamin needed to produce clottting factor 10,9,7,2 in the liver.
Cannot use warfarin during preg. Use heparin.
.
Warfarin antidote
Vit. K levels and FFP.
Don’t eat things with vit. K while using warfarin
Warfarin only affect the synthesis of new clotting factor.
Does nothing on already circulating/made clotting factors.
Warfarin causes a transient hypercoagulable state.
Give Heparin for a couple of days with warfarin.
Heparin antidote?
Protamin Sulfate
How to monitor Heparin, Warfarin and Enoxaparin?
Heparin
Warfarin
Enoxaparin = Factor Xa activity