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3-31-13 > 3-31-13 > Flashcards

3-31-13 Flashcards

1
Q

H. Influenza B causes what in kids?

A

Common cause of Epiglotitis and Otidis media in kids.

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2
Q

H influenza B vaccine tips?

A

Vaccination HiB is conjugated: Toxoid + capsular protein.

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3
Q

What is the purpose of conjugating vaccine such as HiB

A

To stimulate Th2 cell to make cytokines to stimulate B cells to isotype switch.

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4
Q

Attenuated vaccines?

A

Live vaccines that have been weakened.

Ex: MMR

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5
Q

Killed- whole cell vaccines?

A

Killed bacteria vaccines that the organism have been inactivated.
Ex: Samonella and bordatella.

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6
Q

Toxoid vaccines?

A

Made from inactivated bacterial toxins.

Ex: Diphteria and tetanus.

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7
Q

Electrolytes/hormone disturbances in 21 alpha hydroxylase deficiency?

A

Hyponatremia, hypochloremia.
Decreased aldosterone
Hyperkalemia, elevated BUN.
Elevated 17-hydroxyprogesterone levels.

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8
Q

What CREST stands for?

Name antibody found to elevated?

A

Calcinosis. Raynaud phenomenon. Esophageal dysfunction. Sclerodactyly. Telengiectesias.
Anti-Centromere antibody.

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9
Q

Anti-RNP is a good marker for?

A

Mixed connective tissue disease.

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10
Q

Anti-SSA, Anti-SSB, Anti-RAP. Rho-la. good marker for?

A

Sjogran disease.

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11
Q

Anti-dsDNA and Anti-SM marker for?

A

SLE

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12
Q

Anti-SCL-70 good marker for

A

Scleroderma.

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13
Q

C. diphtheria toxin works by?

A

Inactivating Translation Elogantion factor 2 (eEF-2) via ADP-riboxylation.
This inhibits cell protein synthesis.

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14
Q

Fluoxetine drug use for?

A

MC used with Major Depression

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15
Q

Remember that MCC of Pelvic Inflammatory Disease is?

A

Chlamydia and N. Gonnorrhea.

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16
Q

ELISA

A

good test when trying to find out if a person has antibody to a particular thing.

17
Q

Northem used to determine what?

A

RNA levels in a cell.

18
Q

Southern blot used to determine what?

A

Used to study genomic DNA.

19
Q

PCR reactions good for?

A

Ampliflying small pieces of DNA for DNA mapping or sequencing.

20
Q

BRACA-1 gene associated with what?

A

Breast and ovarian cancers. This tumor suppressor gene is located in the chromosome 17q

21
Q

Berry aneurysm is associated with what conditions?

A

Marfan. Ehlers-danlos. APKD. HTN. Smoking.

22
Q

Polymyalgia rheumatic associated with?

A

Temporal arteritis => headaches and jaw claudication.

23
Q

Salicylate intoxication look for first?

A

Tinnitus as the first sign of intoxication.

Acidosis and Hyperventilation occurs after very high levels of intoxication.

24
Q

mental retardation associated with chromosomal breakage think?

A

Fragile X syndrome.
Culture lynphocyte with methotrexate and look for specific breakpoints.
Trinucleotide repeates are the site of breakage and gets worse in each next generation.

25
Q

Acethamenophem OD give?

A

Acetylcysteine=> works by repleneshing glutathione levels = thus protecting the liver from damage.

26
Q

what is the cardiac manifestation involved with SLE?

A

Libman-sacks endocarditis can occur with SLE.

27
Q

Pts with Type DM rely on what mechanism to increase blood sugar?

A

It cannot use Glucagon so it acutly is used epinerphrine and chronically can use cortisol

28
Q

Migratory thrombopheblitis

A

Formation and dissolution of clots secondary to tumors that secrete platelet aggragating factors.
Common seen with pancreatic CA.

29
Q

Generalized transduction

A

requires the presence of a virus to transfer the DNA from one bacterium to another.

30
Q

Conjugation

A

genetic exchange involving cell to cell transfer of DNA. Bacteria sex!

31
Q

Metaformin vs Glipizide to tx diabetes

A

Choose Glipizide if the pt has mild to moderate renal issues. Glipizide undergoes hepatic clearance.

32
Q

Otitis media with bone invasion think?

A

Pseudomonas aeruginosa.

33
Q

Pseudomonas aeruginosa.

A

GNR. Ox +. Produce blue-green pigments.

34
Q

PTH hormone electrolytes?

A

Increase serum calcium.
Increase cAMP present in the Urine.
Decrease phosphate.

35
Q

McArdle disease: chronic exercise intolerance with myalgia, fatigue, painful cramps and

A

Due to Glycogen phosphorylase deficiency.

3-31-13 (3 decks)

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