4/1: Dental Materials - Biocompatibility Flashcards
How is biocompatibility associated with the environment?
Works both ways - material may affect the environment and/or the environment may affect the material
The material must be of benefit to the patient and above all, the patient must be _____________________________
Safe from any adverse reactions
What level can biological reactions take place?
Either at a local level (injection site) OR far removed from the site of contact (systemically adverse Rx from acrylic monomer in a denture (denture stomatitis)
What are other ways that there can be a reaction?
Systemically may not always be readily apparent - dermatological, immune-mediated, neural reactions
What is the most common reaction to dental staff?
Hand/facial dermatitis or respiratory symptoms
What are possible interactions between restorative material and the biological environment?
- Post operative sensitivity
- Toxicity
- Corrosion
- Hypersensitivity/allergy
What is the toxicity of dental materials?
Nanomaterials (size of 1-00nm) growing concern about their biosecurity and crossing the blood brain barrier and going to the central nervous system
What can amalgam or its components cause?
Type IV (usually 24-48 hours after exposure) on the oral mucosa
Who do contact allergies to dental materials affect?
Primarily women
Average age 63 years
What are most common contact allergies to dental materials?
Metals, of which nickel and cobalt were most common allergens
What do denture resins show in dental material allergens?
Mucosal changes, contact stomatitis, and burning sensations of the mouth
Some patients can develop allergic or hypersensitive reactions to even very small quantities of metal such as:
Mercury
Nickel
Cobalt
What can mercury cause to the patient?
direct contact of oral mucosa with this material can cause oral chronic inflammatory lesions on the oral mucosa
What should you ask a patient to see if they are allergic to nickel?
Ask if they can wear costume jewelry
What is this?
Oral lichen planus
What is this?
Amalgam tattoo
What is one of the most common causes of allergic contact dermatitis and produces more allergic reactions than all other metals combined?
Nickel
What are several brands of orthodontic wires made of?
Nickel titanium alloy
What do non-precious metal crowns contain?
High levels of nickel - some as high as 55%
What is this?
Nickel allergy
What is oral allergy syndrome?
Some people with pollen allergies have allergic symptoms around and in the mouth and throat after eating raw fresh fruits, vegetables, nuts, or seeds which contain proteins cross reactive to the pollens
What is this?
Oral hypersensitivity rxn
What is this?
Titanium hypersensitivity
What is sargenti paste for root canals?
Paraformaldehyde
As a dentist, what must you know about materials?
- dental practitioners are responsible for the materials to which a patient will be exposed
- must have knowledge and understanding of the composition of the materials and how they can affect patients
- safest and most effective
- read and understand all inserts that come with materials
What can materials cause?
Irreversible damage causing destruction of CT, bone, nerves, chronic infection and pain