3rd week and placental development Flashcards
Formation of germ layer
Gastrulation
Formation of neural tube:
Neurulation
Germ layer formation occurs in ___ sequence
cranio-caudal
Prochordal plate is formed in the ___ region of the embryo
head region
Prochordal plate is ____ cells of _____
columnar cells of hypoblast
Prochordal plate forms:
buccopharyngeal membrane
Primitive streak is formed in the:
tail end of the embryo
Primitive streak is derived from the :
epiblast
Primitive streak formation starts at the:
end of 2nd week or beginning of 3rd week (14th or 15th day)
Indication of gastrulation
primitive streak formation
Germ layer development:
a) 1st germ layer to develop:
b) 2nd germ layer to develop:
c) 3rd germ layer to develop:
d) 4th germ layer to develop:
a) endoderm (from epiblast)
b) intraembryonic mesoderm (from pritive streak)
c) ectoderm (remains of epiblast after the formation of IEM)
d) neural crest cell (NCC)
Intraembryonic mesoderms spreads throughout the disc except:
prochordal plate and cloacal membrane
All the germ layers are derived from:
epiblast > yolk sac
At the tip of primitive streak, there is :
hensen’s node
Invagination of the hensen’s node proliferation forms:
blastophore/ primitive pit
From primitive pit forms:
notochord formation
Fate of notochord:
disappears
If notochord persists:
Chordoma formation
Remnants of notochord:
nucleus pulposus> apical ligament of dens
Role of notochord:
notochord stimulates formation of :
neural tube
IEM divides into 3 layers:
- paraxial mesoderm
- intermediate mesoderm
- lateral mesoderm
Undivided part of lateral mesoderm:
septum transversum
Septum transversum contributes to the formation of:
- diaphragm
- liver- connective tissue, kupffer cells, sinusoids
- fibrous pericardium
Lateral mesoderm divides into:
splanchnopleuric layer and somatic layer of lateral mesoderm
Paraxial mesoderm forms:
somites
Intermediate mesoderm forms:
urogenital system
lateral mesoderm forms:
body cavities- pleural, pericardial, peritoneal cavity
Somatic layer of lateral mesoderm forms:
appendicular skeleton and parietal layer
splanchnopleuric layer of lateral mesoderms forms:
cardiac and smooth muscles, visceral layer
1st pair of somites appear:
on 20th day
somites added each day:
3 pairs
Number of somites by 5th week/35th day :
45 pairs (42-44 pairs)
Sequence of formation of somites
occipital, cervical, thoracic, lumbar, sacral, coccygeal
Number of somites after 5th week:
37 pairs since some somite sin the occipital and coccygeal region disappear
Parts of somites:
sclerotome and dermomyotome
Sclerotome forms:
axial skeleton- vertebra
Sclerotome divided into:
ventral - forms body of vertebra
lateral - forms vertebral arch and ribs
dorsal - forms spine of vertebra
Failure of fusion of ventral sclerotome:
hemivertebrae
Failure of fusion of dorsal sclerotome:
spina bifida anomalies
Dermomyotome divided into :
Dermatome: forms dermis of skin
Myotome: forms skeletal muscles
Failure of fusion of dorsal sclerotome with tuft of hair over the defect:
spina bifida occulta
Failure of fusion of dorsal sclerotome with the protrusion of meninges over the defect:
meningocele
Failure of fusion of dorsal sclerotome with the protrusion of meninges with spinal cord in it
meningomyelocele
Smooth muscles over dorsal aorta formed by:
splanchnopleuric layer of lateral mesoderm
smooth muscles over iris is formed by:
neurectoderm
smooth muscle over sweat and mammary gland is formed by :
surface ectoderm
Smooth muscle over pharyngeal arch arteries is formed by:
NCC
Formation of blood vessels is called:
angiogenesis
Formation of blood vessels is by :
Mesodermal layers- splanchnopleuric+somatopleuric layer of EEM –> forms blood vessels (tertiary villi)
Tertiary villi is formed by:
3rd week/ 21st day
Anastomosis of blood vessels in the EEM with the IEM is called :
Tertiary villi
Tumor of blood vessels(mesodermal layer)
Angioma
Formation of blood cells:
hematopoiesis
Hematopoiesis is done upto 5th week by:
splanchnopleuric layer of EEM
Hematopoiesis is done from 5th week by:
liver, thymus, bone marrow, spleen
Hematopoiesis in liver occurs upto:
7th month
Placenta is contributed by 2 factors
maternal component: decidua basalis
fetal component: chorionic villi
Uterine endometrium during pregnancy is called:
decidua
Decidua between fetus and myometrium of uterus:
decidua basalis
Decidua between fetus and uterine cavity:
decidua capsularis
Remaining of decidua:
decidua parietalis