3d. Ewing's Sarcoma (Primary Neoplasms)

Question 1

What is a Ewing’s Sarcoma (ES)?

Answer 1

Marrow cell tumor; “round cell”

Question 2

T or F: Ewing’s Sarcoma is uncommon is asians

Answer 2

F (it is uncommon in BLACKS)

Question 3

Age range of ES?

Answer 3

10-25

Question 4

Is ES more common in dudes or dudettes (can you guess by now?)

Answer 4

Dudes

Question 5

Is Pain and swelling more dispersed or local in ES?

Answer 5

Local; local warmth, tenderness, and dilated veins

Question 6

Systemic signs in ES?

Answer 6

Fever, Anemia, Leukocytosis, increased ESR

Question 7

What does ES clinically mimic?

Answer 7

Infection

Question 8

MC location of ES?

Answer 8

Long bones (femur, tibia, fibula, humerus)

Question 9

Classic location in the bone for ES?

Answer 9

Diaphysis

Question 10

Do you normally see a speculated response in an infection?

Answer 10

No, so that is a good way to differentiate between primary malignancy and infection

Question 11

Plain film findings?

Answer 11

Permeative, usually mixed pattern, wide zone of transition

Question 12

Do you usually see a laminated periosteal response?

Answer 12

Not usually, but it is possible (25-50%)

Question 13

Early sign of ES?

Answer 13

Cortical Saucerization

Question 14

ES is the most common primary bone tumor to metastasize to ___?

Answer 14

Bone (frequent and early skeletal mets)

Question 15

Another common mets site for ES?

Answer 15

Lungs

Question 16

Prognosis for ES?

Answer 16

Poor, but improved with earlier diagnosis

Question 17

Treatment?

Answer 17

• Radiation
• Chemotherapy
• Surgical Resection/Amputation