3.CCBs (non-DHP) Flashcards

1
Q

BOX

Diltiazem Verapamil

non-Dihydropyridine CCBs

A

NA

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2
Q

Contra.

Diltiazem Verapamil

non-Dihydropyridine CCBs

A

SBP < 90 mm Hg
Cardiogenic shock
2nd or 3rd AV block
Sick sinus syndrome

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3
Q

Warnings

Diltiazem Verapamil

non-Dihydropyridine CCBs

A

Hypotension
HF (worsen symptoms)

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4
Q

Side effects

Diltiazem Verapamil

non-Dihydropyridine CCBs

A

Edema
Constipation
Gingival hyperplasia

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5
Q

Notes

Diltiazem Verapamil

non-Dihydropyridine CCBs

A

IV:PO does conversions are not 1:1

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6
Q

Drug interactions

Diltiazem Verapamil

non-Dihydropyridine CCBs

A

Other drugs lowering HR (beta-blocker, digoxin, clonidine, amiodarone)
Substrates of 3A4
Moderate 3A4 inhibitors
Substrates of P-gp

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7
Q

Monitor

Diltiazem Verapamil

non-Dihydropyridine CCBs

A

BP
HR
LFTs

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