3.CCBs (non-DHP) Flashcards
1
Q
BOX
Diltiazem Verapamil
non-Dihydropyridine CCBs
A
NA
2
Q
Contra.
Diltiazem Verapamil
non-Dihydropyridine CCBs
A
SBP < 90 mm Hg
Cardiogenic shock
2nd or 3rd AV block
Sick sinus syndrome
3
Q
Warnings
Diltiazem Verapamil
non-Dihydropyridine CCBs
A
Hypotension
HF (worsen symptoms)
4
Q
Side effects
Diltiazem Verapamil
non-Dihydropyridine CCBs
A
Edema
Constipation
Gingival hyperplasia
5
Q
Notes
Diltiazem Verapamil
non-Dihydropyridine CCBs
A
IV:PO does conversions are not 1:1
6
Q
Drug interactions
Diltiazem Verapamil
non-Dihydropyridine CCBs
A
Other drugs lowering HR (beta-blocker, digoxin, clonidine, amiodarone)
Substrates of 3A4
Moderate 3A4 inhibitors
Substrates of P-gp
7
Q
Monitor
Diltiazem Verapamil
non-Dihydropyridine CCBs
A
BP
HR
LFTs