2.CCBs (DHP) Flashcards

1
Q

BOX

Amlodipine Nifedipine ER Nicardipine IR Nicardipine SR Nicardipine IV

Dihydropyridine calcium channel blockers

A

NA

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2
Q

Contra.

Amlodipine Nifedipine ER Nicardipine IR Nicardipine SR Nicardipine IV

Dihydropyridine calcium channel blockers

A

NA

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3
Q

Warnings

Amlodipine Nifedipine ER Nicardipine IR Nicardipine SR Nicardipine IV

Dihydropyridine calcium channel blockers

A

Hypotension
Nifedipine IR: do not use

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4
Q

Side effects

Amlodipine Nifedipine ER Nicardipine IR Nicardipine SR Nicardipine IV

Dihydropyridine calcium channel blockers

A

Peripheral edema
Flushing
Headache
Palpitations/tachycardia
Gingival hyperplasia

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5
Q

Notes

Amlodipine Nifedipine ER Nicardipine IR Nicardipine SR Nicardipine IV

Dihydropyridine calcium channel blockers

A

Amlodipine is one of the safest for HFrEF patients
Nifedipine ER is a choice in pregnancy

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6
Q

Drug interactions

Amlodipine Nifedipine ER Nicardipine IR Nicardipine SR Nicardipine IV

Dihydropyridine calcium channel blockers

A

Other drugs decreasing HR (beta-blocker, digoxin, clonidine, amiodarone)
Substrates of 3A4, avoid grapefruit juice

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7
Q

Monitor

Amlodipine Nifedipine ER Nicardipine IR Nicardipine SR Nicardipine IV

Dihydropyridine calcium channel blockers

A

BP
HR
peripheral edema

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