3B. Probability, Odds and Risk Flashcards

1
Q

what are odds?

A

the number of patients who achieve the end point against the number of patients who did not achieve the end point

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2
Q

what is the equation for odds?

A

Odds = number of patients achieving end point / number of patients NOT achieving end point

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3
Q

what is the equation for the odds ratio?

A

Odds ratio = odds for treatment group / odds for control group

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4
Q

what does it mean if the Odds ratio is less than 1?

A

it means fewer people have recovered from treatment

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5
Q

what does it mean if the Odds ratio is more than 1?

A

it means that more people have recovered from treatment

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6
Q

what is risk fundamentally?

A

a probability

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7
Q

what is the equation for risk?

A

risk = number of patients achieving end point / total number of patients

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8
Q

what is risk ratio

A

risk ratio = risk for one group / risk for another group

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9
Q

what does it mean if risk ratio is 1

A

means that both groups have the same amount of risk

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10
Q

what does it mean if risk ratio is greater than 1

A

means that the risk of the group on the top of the fraction was the greater risk or probability.

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11
Q

what does it mean if risk ratio is less than 1?

A

it means that the risk of the group on the bottom of the fraction was the greater risk or probability

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12
Q

what is absolute risk?

A

the event rate of something happening

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13
Q

what is absolute risk reduction?

A

the difference between the treatment risk and the control risk.

OR

control event rate - Experimental event rate

(treatment risk is the same as experimental event rate and control risk is the same as control event rate)

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14
Q

what is relative risk?

A

the treatment risk of getting ill as a proportion of the control risk of getting ill

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15
Q

what are the 2 forms of the relative risk equation

A

Experimental event rate / control event rate

OR

treatment risk of remaining ill / control risk of remaining ill

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16
Q

what is relative risk reduction?

A

the absolute risk reduction as a fraction of the control absolute risk

17
Q

what are the 2 equations for relative risk reduction?

A

(control event rate - treatment event rate) ÷
control event rate

OR

relative risk reduction = 1 - treatment event rate / control event rate

aka 1 - relative risk

18
Q

what is number needed to treat?

A

the number of people you’d need to treat to achieve the event of interest once (e.g. getting ill)

19
Q

what is the equation of number needed to treat?

A

number needed to treat = 1 / absolute risk reduction