3a. Genome structure content variation Flashcards
The ‘C-value’ paradox
Genome size does not correlate with an organism’s complexity. It is not the number of genes, but the proportion of TEs that accounts for the main differences in genome size among species.
(Grasshopper has a less selective pressure, and because of than can have more ‘junk’ DNA)
Pseudogenes
are nonfunctional segments of DNA that resemble functional genes – they can’t express their properties
Where do new genes come from?
- Gene duplications
- Repetitive sequences
- Amplification of transposons (= a DNA sequence that can change its position within a genome, sometimes creating or reversing mutations and altering the cell’s genetic identity and genome size)
Polyploidy
more than 2 copies per chromosome (more than 3 copies lethal in humans)
Endopolyploidy
replication without cell division
Autopolyploid
the genome consists 2 copies of the diploid genome = tetraploid
(occurs when a polyploid offspring is derived from a single parental species (usually via self fertilisation))
Allopolyploid
diploid set of chromosomes from 2 genetically different parents
(occurs when a polyploid offspring is derived from two distinct parental species)
Paleo- polyploidy
massive gene duplication at one time using a molecular clock
HOX genes
a family of transcription factors, are major regulators of animal development (where come the head, legs, eggs)