3.9 DNA replication/genetic code Flashcards
role of DNA helicase
travels along DNA backbone and catalyses reactions that break hydrogen bonds between bases to unwind and separate the 2 strands
role of DNA polymerase
catalyses formation of phosphodiester binds between free nucleotides and newly exposed bases
stages of semi-conservative replication
- helicase causes two strands of DNA to untwist and separate, exposing the bases
- each strand is used as a template to make 2 new double strands
- new nucleotides pair to exposed bases
- DNA polymerase causes each new chain of nucleotides to be bonded together
- each molecule twists to form double helix
when do mutations occur
when sequences of bases aren’t matched exactly
random and spontaneous
what is the genetic code
the sequences of bases in DNA are ‘instructions’ for sequences of amino acids in protein production
UNIVERSAL
triplet code
code in the base sequences
codon
sequence of 3 bases
codes for amino acid
what is a gene
section of DNA that contains complete set of bases to code for entire protein
why is it a degenerate code
there are 64 different base codons
1 codon = start codon (ensures no overlapping)
3 codons = ‘stop’ codons
amino acids can be coded for by more than one codon