36. Respiratory biophysics & physical examination Flashcards
What is Henry’s law?
At constant temperature, the amount of a given gas that dissolves in a given type and volume of liquid is proportional to the partial pressure of that gas
What is the capillary phenomenon?
capillary pressure difference sustained across the interface between 2 static liquids due to surface tension
Henry’s law equation
p = k * c
Capillary phenomenon equation
dp = 2gamma / R
p : pressure
gamma : surface tension
R : radius of curvature
What doe surface tension result from?
surface tension results from the greater attraction of liquid molecules to each other (due to cohesion) than to the molecules in the air (due to adhesion), causing an inward force at the surface (like an elastic mb)
What is intrapulmonary pressure
Pressure exerted by gases within the alveoli
How does intrapulmonary pressure change in the respiratory cycle?
it decreases as lung volume increases (inspiration)
How does intrathoracic pressure change in the respiratory cycle?
It becomes more negative as the chest wall expands during inspiration
What is the transmural / transpulmonary pressure?
Pressure difference across the chest wall
How many dichotomic division are there
23-25
How many alveoli are there?
About 300 million
Total alveolar area
About 100m²
3 membranes separating the gas exchange surfaces
- Alveolar epithelium
- basal membrane
- Endothelial membrane
What are the 4 lung volumes?
- Tidal volume
- Expiratory reserve volume
- Inspiratory reserve volume
- Residual volume
What are the 4 lung capacities?
- Vital lung capacity
- Inspiratory capacity
- Functional residual capacity
- Total lung capacity
What is functional residual capacity?
Volume of air in the lung after passive expiration
What are the major mechanisms that drive pulmonary ventilation? (3)
- Atmospheric pressure
- Alveolar pressure
- Intra-pleural pressure
What is eupnoe?
Normal breathing (14-16 /min)
What is polypnoe / tachypnoe?
Number of breaths over 16/min