35. Rickets Flashcards
Outline the pathophysiology of rickets
Path = decreased availability of phosphorus and calcium to mineralize the skeletal matrix, leading to growth plate disorganization and accumulation of undermineralized osteoid. This results in growth plate expansion, bone weakening, and skeletal deformities
List the causes of rickets
Vit D def
- malnutrition
- no sunlight
- Celiac disease
- Inflammatory bowel disease
- Cystic fibrosis
- Kidney problems
Ca def
- malnutrition
- vit D def
Hypophosphatemic rickets - rare, genetic
How does rickets present?
- Delayed growth
- Delayed motor skills
- Pain in the spine, pelvis and legs
- Muscle weakness
- Bowed legs or knock knees
- Thickened wrists and ankles
- Breastbone projection
How should suspected rickets be Ix?
Head-to-toe bone exam
X-ray
How should rickets me Mx?
Vit D and calcium supplements
Hypophosphatemic rickets = phosphorus supplements
Brace = position body appropriately as the bones grow
Severe deformity = surgery
What are the possible complications of rickets?
Failure to grow
An abnormally curved spine
Bone deformities
Dental defects
Seizures
