34 Spleen

Question 1

what is special about splenic and short gastric arteries

Answer 1

end arteries

Question 2

where is splenic vein located compared to splenic artery

Answer 2

postern-inferior

Question 3

what does the spleen do

Answer 3

antigen-processing center for macrophages

Question 4

what is the largest producer of IgM

Answer 4

spleen

Question 5

what is the spleen made up

Answer 5

85% red pulp 15% white pulp

Question 6

what does red pulp do

Answer 6

filter for aged or damaged RBCs

Question 7

what causes pitting

Answer 7

removal of abnormalities in RBC membrane

Question 8

what are howell-jolly bodies

Answer 8

nuclear remnants

Question 9

what are heinz bodies

Answer 9

hemoglobin

Question 10

what is culling

Answer 10

removal of less deformable rbis

Question 11

what does white pulp do/contain

Answer 11

immunologic function; contains lymphocytes and macrophages, bacterial clearance, but no preexisting antibodies

Question 12

what does the white pulp remove?

Answer 12

poorly opsonized bacteria, particles, cell debris

Question 13

where does antigen processing occur? between what cells?

Answer 13

white pulp. between macrophages and helper T cells

Question 14

anatomy of the spleen

Answer 14

Question 15

what is tuftsin, what does it do, where is it made

Answer 15

an opsonin. facilitates phagocytosis. produced in spleen

Question 16

what is properdin, what does it do, where is it made

Answer 16

activates alternate complement pathway

produced in spleen

Question 17

where does hematopoiesis occur and when?

Answer 17

occurs in spleen before birth and in conditions like myeloid dysplasia

Question 18

what’s the spleen’s function in terms of platelets

Answer 18

reservoir

Question 19

where are accessory spleens usually found, in what percent?

Answer 19

20%. found at the splenic hilum.