3.4 AIDS/Vaccines Flashcards

1
Q

type ___ hypersensitivity reaction involves IgE

A

I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Type __ hypersensitivity is Organ or cell specific

A

II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

_______ is a disease in which a person develops anti-thyroid antibody

A

Hashimoto’s thyroiditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

_____ is a disease in which a person develops antibodies to intercellular substance of the epithelium

A

Pemphigus Vulgaris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

______________ is a diseaese in which someone develops antibodies to RBCS

A

Autoimmune hemolytic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

antibodies to RBC react against the __ antigen expressed by RBC

A

I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

____________ is a disease in which someone develops an antibody to basement membrane

A

Mucous membrane pemphigoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

__________ is a disease in which a person has an antibody to AcH receptor

A

Myasthenia gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are examples of Type II hypersensitivity diseases?

A

Hashimoto’s thyroiditis
Pemphigus Vulgaris
Autoimmune hemolytic anemia
Mucous membrane pemphigoid
Myasthenia gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Type ___ hypersensitivity reactions are NON-organ specific

A

III

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a type III hypersensitivity disease is _____

A

Lupus erythematosus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Type IV diseases involve ____ and ____

A

CMI and T-cell mediated diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

in type 1 diabetes,_______________ are destroyed by cytotoxic CD8+ T-cells

A

Beta cells in islets of Langerhans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the most common AID?

A

rheumatoid arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are 2 possible treatments for Type IV hypersensitivity diseases?

A
  1. antibody to TNF-alpha
  2. Anti-CD20 antibody
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

which types of hypersensitivity reactions can be associated with autoimmune diseases?

A

II, III, IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

is there a correlation between type I reactions and AIDs?

A

NO

18
Q

_______ immunity is received when you are exposed to microbe or its products

A

Active

19
Q

what are the natural and artificial ways you can acquire active acquired immunity?

A

-Natural: develops after recovering from an infection
-Artificial: intentional administration of toxoids (tetanus)

20
Q

what is the duration of immunity like in killed vaccines vs live vaccines?

A

-killed vaccines = short lived immunity
- live vaccine = long lived immunity

21
Q

what type of vaccine is dangerous to immunosuppressed people?

A

live vaccine

22
Q

______ imunity is given through administration of preformed ABs such as anti-toxins or human gammaglobulin

A

Passive

23
Q

what are the natural and artificial ways you can acquire passive immunity?

A

-Natural: placental transfer of anti bodies
-Artificial: anti-toxins (tetanus), human gammaglobulin, select monoclonal antibodies

24
Q

is immunity limited or infinite with passive immunity?

A

limited

25
Q

______ are substances that non-specifically enhance the immune response by:

A

Adjuvants

26
Q

how do adjuvants work? (2 ways)

A
  • causeProlonged exposure to antigen
  • Initiating inflammatory response at site of inoculation
27
Q

what are 3 examples of adjuvants?

A
  1. Alum (part of HepB vax)
  2. Freunds adjuvant (animal use only)
  3. Matrix M (tree bark for COVID19 NOVAvax)
28
Q

______ = donor and recipient are same person

A

Autograft

29
Q

______ = donor and recipient are genetically identical

A

Isograft

30
Q

_________ = donor and recipient are of same species but genetically different

A

Allograft

31
Q

______ = donor and recipient are of different species

A

Xenograft

32
Q

acute graft rejections are mediated by ______

A

t-cells

33
Q

hyperacute graft rejections are mediated by ______

A

antibodies

34
Q

what type of reaction is hyperacute graft rejection an example of?

A

type II

35
Q

_________occurs when donor lymphocytes in the donor graft attack recipient cells

A

Graft vs Host disease

36
Q

if you are blood type A, you have __ antibodies, and ___ antigens

A

Anti-B antibodies
A antigen

37
Q

if you are blood type AB, you have __ antibodies, and ___ antigens

A

NO ANTIBODIES
A and B antigens

38
Q

if you are blood type O, you have __ antibodies, and ___ antigens

A

Anti-A and Anti-B antibodies
NO ANTIGENS

39
Q

__________ can occur when a pregnant woman (Rh-) has anti-D/IgG antibody to Rh) and her fetus is _____

A

Erythroblastosis fetalis, Rh+

40
Q

Rh antigens: found on RBC of ___% population in US

A

85%