3.4 Flashcards

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1
Q

What are neuron’s?

A

Cells which make up the nervous system are
called neurons. They transmit information
through electrical impulses.
• They are made up of a nucleus, cell
membrane and cytoplasm like all other animal
cells. However, they are specialised for their function

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2
Q

Impulse conduction

A

Nerve impulses only travel in one direction
along a neuron.
Fibres that conduct impulses towards the cell
body are called dendrites & dendrons
Fibres that conduct impulses away from the
cell body are called axon

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3
Q

3 Types of Neuron

A

Inter Neuron Sensory Neuron Motor Neuron

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4
Q

What is The Myelin Sheath

A

• Axons have myelin sheaths around them. This is a
fatty covering which protects the nerve and insulates it.

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5
Q

What is myelination?

A

When you are born, myelin sheaths are not fully
developed. The process of myelination continues
from birth to adolescence. This means that as a baby or toddler, you are not as rapid or
coordinated as an adult.

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6
Q

What disease most commonly destroys the myelin sheath

A

MS

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7
Q

What are glial cells ?

A

• Glial cells are cells which sit around or beside
neurons.
• They have 2 main roles:
– Physical support of neurons
– Production of myelin sheath

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8
Q

How can electrical impulses pass through a synapse?

A

a chemical called a neurotransmitter must be used

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9
Q

How do neurotransmitters work?

A

• Neurotransmitters are stored in vesicles (small
pockets) on the end of each axon at each
presynaptic neuron.
• They are released into the synaptic cleft when
a nerve impulse arrives at the end of the axon.
• They diffuse across the synaptic cleft and bind
to receptors on the dendrite of the post synaptic neuron

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10
Q

What happens if the neurotransmitter left in the cleft.

A

there would be
continuous stimulation and the system could not respond to new signals

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11
Q

How are Neurotransmitters removed?

A

Neurotransmitters are removed in 2 ways:
– Enzyme degradation:
• Acetylcholine is a neurotransmitter which is broken
down by an enzyme after it’s been used.
– Re-uptake:
• Nor-adrenaline is a neurotransmitter that is reabsorbed by the pre synaptic membrane

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12
Q

What are Endorphins?

A

• Endorphins are
neurotransmitters that stimulate neurons
involved in reducing the intensity of pain.

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13
Q

When do the Production of endorphins increase?

A

following
severe injury, prolonged continuous exercise,
stress and eating certain foods.

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14
Q

What is Dopamine?

A

Dopamine is a neurotransmitter which induces
(gives) feelings of pleasure and reinforces
particular behaviour by activating a reward
pathway in the brain.

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15
Q

What is the reward pathway

A

• The reward pathway has neurons which respond
to dopamine.
• The reward pathway activates when people do
things that are beneficial to them, e.g. eating when hungry.

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16
Q

Drugs as Medicines

A

Some medicines affect the way in which
neurotransmitters function and can be used to treat some conditions

17
Q

What are agonist drugs

A

Agonist drugs mimic natural neurotransmitters
and can therefore enhance their action

18
Q

What are Antagonist drugs

A

Antagonist drugs block the action of natural
neurotransmitters and prevent nerve impulses
from passing to synapses

19
Q

What do other drugs do to treat some affections ?

A

Other drugs act by inhibiting the enzymes that
degrade neurotransmitters or by
inhibiting reuptake of the neurotransmitter at
the synapse causing an enhanced effect.

20
Q

What are Recreational Drugs

A

Recreational drugs can also be agonists or
antagonists.
• They can alter a person’s mood or behaviour
because they affect neurotransmission at
synapses. Drugs have different effects on
different people.

21
Q

What can repeated use of antagonist drugs cause?

A

sensitisation – an increase in the number and
sensitivity of receptors. This sensitisation
leads to craving of the drug and causes drug addiction

22
Q

What can repeated agonist drugs cause?

A

desensitisation – a decrease in the number
and sensitivity of receptors. This
desensitisation leads to drug tolerance which
means an individual must take more of the drug to get the desired affect.

23
Q

What Agonist drugs can lead to drug tolerance ?

A

Agonist drugs which can lead to drug
tolerance include nicotine, cocaine and MDMA (ecstasy)

24
Q

What Antagonist drugs can lead to drug addiction ?

A

heroin and morphine, a common painkiller.