3.3 Digestion And Absorption Flashcards
Oesophagus
Thin epithelial layer No villi Glands produce mucus - lubricate food Thick muscular layer Muscles propel food via peristalsis
Duodenum
Pancreas - pancreatic juice - enzyme
Liver - bile - contains bile salts which aid lipid digestion and sodium hydrogen carbonate to neutralize acid
Low villi
Illeum and jejunum
Mucosa and sub-mucosa contain glands which secrete enzymes mucus and alkali
Folding of mucosa, villa and micro villa increase SA
Peristalsis
Large intestine
Caecum Appendix Colon Rectum Water absorbed forms semi solid faeces Mucosa contain villi but no microvilli Glands secrete mucus Anal sphincter - releases faeces
Carbohydrate digestion - amylase
Produced in salivary glands and pancreas
Secreted in duodenum and buccal cavity
Catalysts the break down of starch into disaccharides by hydrolises reactions which beak down alternative glyocosidic bonds
Carbohydrate digestion - membrane bound disaccharidase
Enzymes attached to cell membranes of epithelial cells
Produced in the walls of the illeum
lining the ileum
Breaks disaccharides into monosaccharides
Absorption of monosaccharides
- Na+ actively transported out of epithelial cells into the blood via Na-K pump
- High conc of Na+ in lumen than in epithelial cells
- Na+ diffuse into epithelial cells down conc gradient coupled with a glucose or a-acid through a protein carrier (cotransporter)
- Glucose passes into blood plasma via facilitated diffusion
Protein digestion
Endopeptidase - hydrolyses peptide bonds within proteins
Pepsin, trypepsin, chymotrepsin
Exopeptidase - hydrolyses peptide bonds at the end of proteins
Dipeptidase - hydrolyses peptide bonds between 2 amino acids - cell membrane of epithelial cells
Digestion of lipids
Bile salts - produced by liver, emulsification occurs in intestinal lumen
Emulsifies lipids to increase SA so lipase can digest faster
Pancreatic Lipase - prod by pancreas, secreted in s intestine
catalyses the breakdown of lipids in monoglycerides and fatty acids - hydrolyses of ester bonds- products attach to bile salts to form micelles - easier diffusion
Absorption of lipids
Fatty acids and monoglycerides enter cell via diffusion
They resynthesise into triglycerides in the endoplasmic reticulum
The are repackaged with cholesterol and phospholipids in protein coated chylomicrons
These are Incapsuled in a vesicle which are released through the cell membrane via exocytosis in the lymphatic system