3.2 Lymphoid Tissue Flashcards
Lymphatic system is comprised of
Lymphatic vessels
Secondary lymphoid tissue
Lymph vessel example
Thoracic duct
Axillary nodes
Intercostal vesses
Lymphoid tissue is comprised of
Primary
Secondary
Tertiary
Primary lymphoid tissue
Make up primary lymphoid organs: the site of lymphopoiesis (production of lymphocytes)
Lymphocyte examples
B cells
T cells
NK Cells
Primary lymphoid organs examples
Thymus
Bone marrow
Fetal liver
Site of lymphopoiesis
What comprise the adaptive immune response
B cells and t cells
Hallmarks (ability) of the adaptive immune response
Specifity- vast range of unique b and T cell receptors
Memory- rapid expansion in response to second encountee
Humoral response relates to
B lymphocytes
Cell mediated response relates to
T lymphocytes
Sites of haemopoiesis
Bone marrow is primary site
Foetus all bones and liver/spleen
Adult mostly flat bones
Where is the b cell repertoire generates
Bone marrow
(Final maturation occurs in the periphery)
Repertoire
Range of genetically distinct b and T cell receptors present in a host
Larger repertoire
Recognises more threats
Where do T cells mature
Thymus (migrate from bone marrow)
Where does T cell selection occur
Thymus
Steps of T cell selection
Stepwise differentiation:
Positive selection
Negative selection
Final selection and exit
Positive selection in T cell selection
Can the T cell receptor signal (identify foreign antigens)