3.1 COVID-19 Flashcards
When is the first cases of COVID?
8 December 2019
First report of 27 cases of pneumonia with unknown cause in Wuhan China
31 December 2019
China announced the identification of a novel coronavirus as the causative agent of the pneumonia outbreak
9 January 2020
Case of a traveler from Wuhan was confirmed in Thailand
13 January 2020
Wuhan was locked down
21 January 2019
The coronavirus spead to all 34 provinces across China
29 January 2020
WHO declared a PHEIC alert
30 January
WHO risk assessmnet increased to very high on the global level
28 Feb 2020
ICTV named virus SARS-CoV-2 and WHO named disease COVID-19
11 Feb, 2020
WHO defined COVID-19 as a pandemic
11 March 2020
39 year old female had symptoms of cough and sore throat, and Chinese national
Jan 25 2020
44-year-old male, had sumptoms of fever, cough, and chills symptoms. Chinese national
Jan 31, 2020
What are the 2 large genes of COVID 19?
ORF1a
ORF1b
(Open reading frame)
ORF1a and b encodes the 16 structural proteins of the virus
T or F
F
Nonstructural
Nonstructural proteins works on the transcription and replication of the virus
T or F
T
NSP3 = 3CL-protease
NSP5 = papsin-like protease
T or F
F
Baligtad
Structural genes are the ones that encodes the structural proteins of the virus
T or F
T
What protein helps in distinguishing virus similar to SARS-CoV-2?
Accessory protein
Is a critical component of the COVID-19 response
Diagnostic testing
Diagnostic testing is a critical component of the COVID-19 response, as it can be used to:
- Confirm infection in patients who fulfill COVID-19 clinical criteria
- Rapidly screen suspected cases
- Screen for infection in asymptomatic contacts of confirmed COVID-19 cases
- Determine exposure to the virus to understand the true extent of the outbreak, map the pandemic across counties and monitor trends
Which of the following is wrong?
None
Are foreign molecular structures that can trigger an immune response
Antigen
Is a protein made by the body’s immune system that can recognize and target an antigen for destruction
Antibody
Use: to detect active SARS-CoV-2 infection
Target: Viral genetic material
Method: Amplification of small amounts of the viral genome until reaching detectable levels
Location: Lab
Molecular test
Use: to detect active SARS-CoV-2 infection
Target: Viral proteins
Method: Capture antigens on a test strip causing color change
Location: Pont of care
Antigen tests
