30 - Hematologic System Flashcards
duodenum
iron absoprtion
gastric/gastrectomy
parietal cells> less intrinsic factor> B12 deficiency
ileum
B12/cobalamin absorption
common cause of hematemesis
peptic ulcer
non tender consistently swollen lymph nodes
cancer
enlarged tender lymph nodes
infection
prominent symptom of hemotologic problems
fatigue
Hgb in elderly
women: usually normal
men: slight decrease
MCHC in elderly
slight decrease
MCV mean corpuscular volume in elderly
slight increase
platelets in elderly
unchaged number
-possible increase in adhesiveness
WBC in elderly
normal numbers but
decreased response to iinfection
Iron studies in elderly
EPO: may be INCR
ferritin: INCR
serum iron: DECR
total iron-binding capacity: DECR
erythrocyte sedimentation rate ESR in elderly
significant INCREASE
aching bones could indicate
expanding bone marrow> leukemia
purple mottles face, nose, fingers or toes
erythrocytosis
-causes small vessel oclussion
palpable liver could indicate
leukemia
cirrhosis
iron overload fr sickle cell
thalassemeia
palpable spleen could indicate
anemia thrombocytopenia leukemia lymphomas leukopenia
distended abdomen
lymphoma
blurred vision
anemia, leukocytosis, polycythemia, thrombocytopenia
conjuctival pallor
low Hgb/anemia
hypertension
early anemia - compensatory mechanism
orthostatis, HR>20bpm, incr BP >20 from changing positions
anemia
low blood volume
paresthesia of feet or hands
B12 deficiency
epistaxis-bleeding fr nares/nose
low platelet counts
peripheral smear
looks at morphology (shape + appearance)
bone marrow biopsy
- full eval of hematopoiesis
- ability to get specimens for cytopathologic + chromosomal analysis
complication of biopsy
hemorrhage (maybe be due to leukopenic) or
infection (if pt is thrombocytopenic)
molecular cytogenetics + gene analysis require samples from…
bone marrow, lymph nodes, or CSF
normal Hgb
F: 12-16g/dL
M: 14-18 g/dL
normal Hct (packed cell volume of RBC_
F: 37-47%
M: 42-52%
normal RBC count
F: 4.2-5.4million/uL
M: 4.7-6.1
MCV
sixe of RBC
80-95fL
platelet count
150-400million/L