3- TISSUE RENEWAL, REGNERATION, and REPAIR

Question 0

The process by which there is extensive deposition of collagen.

Answer 0

Fibrosis

Question 1

Results in the complete restitution of the lost damage or tissue.

Answer 1

Regeneration

Question 2

The following are examples of labile tissues EXCEPT:

A. Skin epithelia
B. Oral cavity
C. Parenchymal cells of the liver
D. Lining mucosa of all the excretory ducts

Answer 2

C. Parenchymal cells of the liver

Question 3

Mechanism of stem cells in which with each stem cell division, one of the daughter cells retains its self-renewing capacity while the other enters differentiation.

Answer 3

Obligatory asymmetric replication

Question 4

Stem cell mechanism in which there is a balance between self-renewing and differentiated cells.

Answer 4

Stochastic differentiation

Question 5

A change in differentiation of a cell from one type to another is known as ________________.

Answer 5

Transdifferentiation

Question 6

The capacity of a cell to transdifferentiate into diverse lineages is referred to as ___________.

Answer 6

Developmental plasticity

Question 7

Somatic stem cells generate rapidly dividing cells called __________.

Answer 7

Transit amplifying cells

Question 8

The liver contains stem cells/progenitor cells in the _____________.

Answer 8

Canals of Hering

Question 9

Neural precursor cells are found in which two areas of the adult brain.

Answer 9

Subventricular zone and dentate gyrus of the hippocampus

Question 10

This is the rate limiting step for replication in the cell cycle.

Answer 10

Restriction point between G1 and S.

Question 11

This step in cell cycle monitors the integrity of DNA BEFORE replication.

Answer 11

G1/S checkpoint

Question 12

Aids in cell scattering and proliferation.

Answer 12

HGF/Scatter factor

Question 13

Most potent growth factor for vasculogenesis and angiogenesis.

Answer 13

VEGF

Question 14

Growth factor responsible for migration and proliferation of fibroblasts, smooth muscles

Answer 14

PDGF

Question 15

Growth factor that acts as a growth inhibitor and a potent fibrinogenic agent.

Answer 15

TGF-B

Question 16

The following are biochemical pathways that utilize intrinsic tyrosine kinase activity EXCEPT:

A. PI3 Kinase Pathway
B. MAP-kinase Pathway
C. IP3 Pathway
D. cAMP Pathway

Answer 16

D. cAMP Pathway

Question 17

Mobilization of endothelial stem cells and has a role in inflammation.

A. VEFGR-1
B. VEFGR-2
C. VEFGR-3
D. None of the above

Answer 17

A. VEFGR-1

Question 18

Acts on lymphatic endothelial cells to induce lymphangiogenesis.

A. VEFGR-1
B. VEFGR-2
C. VEFGR-3
D. None of the above

Answer 18

C. VEFGR-3

Question 19

Located in endothelial cells and many other cells types and considered to be the main receptors for vasculogenic and angiogenic effect on VEGF.

A. VEFGR-1
B. VEFGR-2
C. VEFGR-3
D. None of the above

Answer 19

B. VEFGR-2

Question 20

Also known as the wear and tear pigment.

Answer 20

Lipofuschin

Question 21

Provide resilience and lubrication to many types of CT (cartilage in joints).

Answer 21

Hyaluronan

Question 22

This is the most abundant glycoprotein in BM.

Answer 22

Laminin

Question 23

Mobilization of endothelial stem cells and has a role in inflammation.

A. VEFGR-1
B. VEFGR-2
C. VEFGR-3
D. None of the above

Answer 23

A. VEFGR-1

Question 24

Acts on lymphatic endothelial cells to induce lymphangiogenesis.

A. VEFGR-1
B. VEFGR-2
C. VEFGR-3
D. None of the above

Answer 24

C. VEFGR-3

Question 25

Located in endothelial cells and many other cells types and considered to be the main receptors for vasculogenic and angiogenic effect on VEGF.

A. VEFGR-1
B. VEFGR-2
C. VEFGR-3
D. None of the above

Answer 25

B. VEFGR-2

Question 26

Also known as the wear and tear pigment.

Answer 26

Lipofuschin

Question 27

Provide resilience and lubrication to many types of CT (cartilage in joints).

Answer 27

Hyaluronan

Question 28

This is the most abundant glycoprotein in BM.

Answer 28

Laminin