2. thyreotoxische Krise Flashcards

1
Q

(thyreotoxische Krise)

Definition

A

Exazerbation einer Hyperthyreose

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2
Q

(thyreotoxische Krise)

Ätiologien (4)

A
  • Iodexposition
  • schwere Erkrankungen
  • Absetzen thyreostatischer Medikamente
  • Schilddrüsen-OP in hyperthyreotem Zustand
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3
Q

(thyreotoxische Krise)

Symptome:

Stadieneinteilung nach Hermann (3)

A

I. Symptome einer Hyperthyreose

II. + Bewusstseinsstörungen

III. + Koma

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4
Q

(thyreotoxische Krise)

Score

A

Burch-Wartofsky

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5
Q

(thyreotoxische Krise)

Burch-Wartofsky-Score: Zweck

A

Einschätzung
der Wahrscheinlichkeit
und des Schweregrades
einer thyreotoxischen Krise

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6
Q

(thyreotoxische Krise)

Burch-Wartofsky-Score: Auswertung (2)

A

> 25: thyreotoxische Krise möglich

> 45: thyreotoxische Krise sehr wahrscheinlich

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7
Q

(thyreotoxische Krise)

medikamentöse Therapie (4)

A
  • Thionamiden + Natriumperchlorate
  • Propranolol
  • Prednisolon
  • NMH
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8
Q

(thyreotoxische Krise)

Perchlorate: Wirkung

A

Hemmung der Iodidaufnahme in die Schilddrüse

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9
Q

(thyreotoxische Krise)

Propranolol: Wirkung (2)

A
  • Hemmung der Konversion von T4 in T3
  • Senkung des Tremors und der Agitation
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10
Q

(thyreotoxische Krise)

Prednisolon: Wirkung

A
  • Hemmung der Konversion von T4 in T3
  • Nebennierenrindeinsuffizienz
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11
Q

(thyreotoxische Krise)

NMH: Wirkung

A

Thromboseprophylaxe

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12
Q

(thyreotoxische Krise)

interventionelle Therapie: Indikation

A

bei bedrohlicher thyreotoxischer Krise

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13
Q

(thyreotoxische Krise)

interventionelle Therapie: Verfahren (2)

A
  • Plasmapherese
  • Notfall-Thyreoidektomie
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