3. thyreotoxische Krise Flashcards

1
Q

(thyreotoxische Krise)

Definition

A

Exazerbation einer Hyperthyreose

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2
Q

(thyreotoxische Krise)

Ätiologien (4)

A

1-Iodexposition

2-schwere Erkrankungen

3-Absetzen thyreostatischer Medikamente

4-Schilddrüsen-OP in hyperthyreotem Zustand

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3
Q

(thyreotoxische Krise)

Symptome: Stadieneinteilung nach Hermann (3)

A

I-Symptome einer Hyperthyreose

II-+Bewusstseinsstörungen

III-+Koma

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4
Q

(thyreotoxische Krise)

Score

A

Burch-Wartofsky

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5
Q

(thyreotoxische Krise)

Burch-Wartofsky-Score: Zweck

A

Einschätzung der Wahrscheinlichkeit und des Schweregrades einer thyreotoxischen Krise

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6
Q

(thyreotoxische Krise)

Burch-Wartofsky-Score: Auswertung (2)

A

> 25: thyreotoxische Krise möglich

> 45: thyreotoxische Krise sehr wahrscheinlich

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7
Q

(thyreotoxische Krise)

Therapie: medikamente (4)

A

1- Thyreostatika

2- Propranolol

3- Prednisolon

4- niedermolekulares Heparin (NMH)

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8
Q

(thyreotoxische Krise)

Thyreostatika: Gruppen (2)

A

1- Thionamiden

2-Perchlorate

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9
Q

(thyreotoxische Krise)

Perchlorate: Mittel der Wahl

A

Natriumperchlorat

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10
Q

(thyreotoxische Krise)

Perchlorate: Wirkung

A

Hemmund der Aufnahmen von Iodid in die Schilddrüse

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11
Q

(thyreotoxische Krise)

Propranolol: Ziel

A

Senkung des Tremors und der Agitation

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12
Q

(thyreotoxische Krise)

Propranolol: Wirkung

A

Hemmung der Konversion von T4 in T3

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13
Q

(thyreotoxische Krise)

Prednisolon: Wirkung

A

Hemmung der Konversion von T4 in T3

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13
Q

(thyreotoxische Krise)

Prednisolon: Ziel

A

Nebennierenrindeinsuffizienz

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14
Q

(thyreotoxische Krise)

NMH: Ziel

A

Thrombolyseprophylaxe

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15
Q

(thyreotoxische Krise)

Verfahren vei bedrohlicher thyreotoxische Krise (2)

A

1- Plasmapherese

2- Notfall-Thyreoidektomie