3. The Cell Cycle & Mitosis Flashcards
What is the cell cycle?
The life of a cell from the time it is first formed during cell division of the parent cell until its own division into daughter cells.
What is the Genome?
The sun total of an organism’s DNA.
What is Cell Division?
The reproduction of cells to produce more of their own.
3 benefits of cell division?
- Repair of damaged tissue
- Growth
- Reproduction
What are somatic cells?
All body cells except the gametes.
What are gametes?
Reproductive cells (sperm and egg)
What is the centromere?
Area of a chromosome where two sister chromatids are joined.
What are the phases of the cell cycle?
Interphase, Mitotic Phase and Cytokinesis
What is interphase?
The first part of the cell cycle that consists of 90% of the process, where the cell grows and duplicates genetic material in preparation for cell division.
How many phases does interphase have?
3
What are the three phases of interphase?
G1 Phase, S Phase, G2 Phase
What is G1 Phase?
In Gap 1 Phase, the cell experiences intense metabolic changes, growth and duplication of non-chromosomal organelle in preparation for cell division.
What is Synthesis Phase?
Replication of DNA in preparation for cell division.
What is G2 Phase?
In Gap 2 phase, the cell continues growth and metabolic changes as materials necessary for mitosis and cytokinesis assemble and simultaneously double checks all duplicated chromosomes for errors, making necessary repairs in preparation for cell division.
What is Mitotic (M) Phase?
A stage in the cell cycle in which newly formed DNA is separated and two new cells with the same number of chromosomes and genetic material formed.
What are the 5 stages of Mitosis?
PpMAT
Prophase, Prometaphase, Metaphase, Anaphase, Telophase
What is Prophase?
- The nucleoli disappears
- The chromatin fibres condense
- Chromosomes appear as sister chromatids
- Mitotic Spindle forms
- Centrosomes move away from each other, lengthening Microtubules between them.
What is the Mitotic Spindle?
Composition of centromeres and Microtubules.
What is Prometaphase?
- The nuclear envelope is disintegrated
- Microtubules are permitted to extend to the chromosome and attach to the kinetochores.
- Nonkinetochore microtubules interact with their opposing partners on the opposite pole, further lengthening the cell.
What is a Kinetochore Microtubule?
A microtubule attached at the kinetochore of a chromosome.
What is metaphase?
- Centrosomes are at opposing poles of the cell.
- Chromosomes are lined up along the metaphase plate.
- Each chromosome, the kinetochores are connected to the kinetochores microtubule coming from the opposing pole.
What is the metaphase plate?
A plane equidistant between the two Mitotic spindle poles.
What is anaphase?
- Cohesions holding sister chromatids together split.
- the two new daughter chromatids migrate to opposing ends of the cell as the Microtubules shorten.
What is telophase?
- two daughter nuclei form
- nuclear envelope arise
- nucleoli reappear
- the chromosomes decondense