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ICM - Exam 1 > 3 - Schizophrenia > Flashcards

3 - Schizophrenia Flashcards

1
Q

schizophrenia incidence and mean age of onset

A

1%

age 15-25

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2
Q

Components of the MSE that are affected in schizophrenia

A

Thought process/form

Thought content

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3
Q

schizophrenia is a disorder of __________

A

impaired thought

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4
Q

schizophrenia involves both ___ and ___ symptoms

A

Positive (hallucinations, delusions, disorganization)

Negative (restricted or imappropriate affect, avolition, alogia)

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5
Q

Alogia =

A

Content or volume of speech is reduced

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6
Q

schizophrenia also involves impairment of ______

A

cognition

-attention, info processing, verbal memory

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7
Q

Delusions cause patients to think that….

A

people are reading their thoughts or plotting against them

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8
Q

A common problem in schizophrenia is the lack of ____ into the condition

A

insight

Not a willful denial but a part of the disease process

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9
Q

Single diagnostic feature of schizophrenia

A

There isn’t one

Also no confirmatory lab test

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10
Q

Clinical diagnosis of schizophrenia is based on ___ and ____

A
  • Presence of a pattern of Sx
  • Longitudinal picture
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11
Q

Criteria for schizophrenia (A-E)

A

A. Two or more of the following : Delusions, Hallucinations, Disorganized speech, Disorganized or catatonic behavior, Negative Symptoms)

B. Interpersonal or psychosocial dysfunction

C. 6 continuous months with 1 month of “A” symptoms

D. Not due to other mental illness

E. Not due to other substances or medical condition

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12
Q

___, ___, and ___ are abnormal in schizophrenia

A

Attitude (suspicious, resistive, negative, guarded, hostile)

Appearance

Behavior

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13
Q

Mood and affect (subjective and objective)

A

Subjective = depressed and poorly described

Objective = FLAT, irritable, angry, hostile

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14
Q

Disordered thought process in schizophrenia includes… (7)

A
  1. Loose associations
  2. Tangential thoughts
  3. DECREASED spontaneity
  4. Poverty of thought
  5. Alogia
  6. Neologisms
  7. Clang associations
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15
Q

What are clang associations

A

characterized by association of words based upon sound rather than concepts.

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16
Q

Disordered thought content in schizophrenia includes… (7)

A
  1. Distortion of reality
  2. Psychotic
  3. Grandiose
  4. Thought insertion
  5. Delusions of thought broadcasting
  6. Paranoid delusions
  7. Auditory hallucinations
17
Q

Mental status abnormalities in schizophrenia

A

Insight (no understanding that they have disease)

Judgement

Intellect (reduced memory, future recall, complex reasoning)

18
Q

There is evidence for accelerated loss of ___ in early onset Schizophrenia

A

Grey matter

19
Q

4 stages of illness

A

Premorbid

Prodromal

Onset/deterioration

Residual/Stable

20
Q

schizophrenia is associated with how much reduction in life expectancy?

A

up to 20%

(about 15 years for each men and women)

21
Q

Top five comorbid conditions

A

Emphysema

Chronic bronchitis

Asthma

Liver problems

Kidney dysfunction

22
Q

two thirds of excess mortality in schizophrenia is attributable to ______

A

natural causes

23
Q

75% of diagnosed schizophrenia patients are…

A

cigarette smokers

24
Q

___% of schizophrenia patients are unemployed

A

73%

25
Q

Downward drift hypothesis

A

Patients tend to enter a lower socioeconomic status after Dx

26
Q

___% of schizophrenics are homeless

A

11%

27
Q

Of prison inmates, __% are mentally ill and __% are actively psychotic

A

20%, 5%

28
Q

Anosognosia

A

Lack of insight, common prominent finding in schizophrenia (up to 90%)

29
Q

Anosognosia is due to

A

neuropsychiatric abnormality within the brain’s frontal and parietal lobes

30
Q

Stigma involved in schizophrenia

A

10-25% less likely to get interventions following AMI

25% of schizophrenics who have hyperlipidemia are likely to get a prescription for cholesterol drugs

31
Q

Medical model vs recovery model

A

Medical = goal s to relieve symptoms to cure

Recovery = to relieve symptoms to improve function

32
Q

Recovery Treatment (wraparound) includes (5)

A
  • Medication
  • Cognitive psychotherapies
  • Case management
  • Counseling/Therapy
  • Psychosocial rehab
33
Q

Psychosocial rehab goal is…

It includes…

A

Goal = lower stigma, integrate into society

Supportive housing, Job rehab, living skills and social skills training, Symptom management, recreation opportunities

34
Q

First Gen Antipsychotics

A

Chlorpromazine

Thioridazine

Perphenazine

Molindone

Loxapine

Fluphenazine + Haloperidol

35
Q

Sides of 1st gen antipsychotics

A

Sedation, Parkinsonian syndrome (due to DA antagonism)

36
Q

Second gen antipsychotics

A

Seroquel (quetiapine), Zyprexa (olanzapine), Abilify (aripiprazole)

**fewer extrapyramidal effects, but Insulin resistance and Diabetes still present.

ICM - Exam 1 (8 decks)

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