3- pathology review Flashcards
what are features of soft tissue tumours
may present as a lump or swelling
- may be associated pain or discomfort
- wide range of lesions
- superficial lesions less likely to be malignant
what is a ganglion cyst
Lump near a joint capsule or tendon sheath which commonly arise around the wrist. It is due to a degenerative change within connective tissue
what is a ganglion cyst histologically
space within myxoid material
how are synovial cysts formed
they can result from herniation of synovial or bursal enlargement
what is nodular fasciitis
Nodular fasciitis is a fast-growing lump in your soft tissue. It is caused by cellular proliferation of fibroblastic and myofibroblastic cells.
who is nodular fasciitis found in
young adults , upper extremity
what is the pathology of nodular fasciitis
- superficial or deep
- usually less than 5cm
- circumscribed - usually
- very cellular
- plump cells; stellate and spindle
- mature towards the periphery
- haemorrhage
what is myositis ossificans
Myositis ossificans is a condition where bone tissue forms inside muscle or other soft tissue after an injury.
what is superficial fibromatoses
Superficial fibromatosis is a non-cancerous tumour made up of a specialized type of connective tissue called fibrous tissue
what are features of superficial fibromatoses
- common
- M>F
- average age 60
- idiopathic
- recognised associations: alcohol, anticonvulsants
what is Dupuytrens pathology
- firm grey and white tissue
- nodules and fascicles
- bland fibroblasts
- dense collagen
what is deep fibromatosis
Deep fibromatosis or desmoid tumor (DF/DT) is a low-grade, soft tissue lesion that is notable for its infiltration and local recurrence and its inability to metastasize.
who often gets deep fibrzomatosis
- young adults (teenage to 30)
where is deep fibrzomatosis usually found
sites:
- musculo-aponeurotic tissue of abdominal wall
- mesenteric tissue
- limb girdles
what is tenosynovitis
giant cell tumour of tendon sheath
- digits and wrist
- reactive proliferation
- excise and rarely occur
pigmented villonodular synovitis
- similar histology
- large joints
- more likely to occur
