cortex - rheumatology

Question 1

what does arthropathy mean

Answer 1

disease of the joint

Question 2

what does arthritis describe

Answer 2

inflammation of the joint

Question 3

why are auto-antibodies produced

Answer 3

generated by the immune system against the body’s own proteins, usually within cells

Question 4

what are anti-CCP antibodies associated with

Answer 4

rheumatoid arthritis

Question 5

what are anti-nuclear antibodies (ANA) associated with

Answer 5

• SLE
• Sjogrens syndrome
• Systemic sclerosis
  MCTD
• Autoimmune liver disease

Question 6

what are anti-double stranded DNA antibodies (dsDNA) associated with

Answer 6

Systemic lupus erythematosus (SLE)

Question 7

what are anti-Sm antibodies associated with

Answer 7

Systemic lupus erythematosus

Question 8

what are anti-Ro antibodies associated with

Answer 8

• Systemic lupus erythematosus

- Sjogrens syndrome

Question 9

what is anti-la antibody associated with

Answer 9

Sjogrens syndrome

Question 10

what is anti-centromere antibody associated with

Answer 10

systemic sclerosis (limited)

Question 11

what is anti-Scl-70 antibody associated with

Answer 11

systemic sclerosis (diffuse)

Question 12

what is anti-neutrophil cytoplasmic antibody (ANCA) associated with

Answer 12

small vessel vasculitis ( GPA, EGPA, MPA)

Question 13

what is seen on an X-ray of a patient with osteoarthritis

Answer 13

L- loss of joint space
O- osteophytes
S- sclerosis
S- subchondral cysts

Question 14

inflammatory arthropathies can be classified into 4 broad groups what are they

Answer 14

seropositive, seronegative, infectious and crystal deposition disorders

Question 15

what joints are affected in RA

Answer 15

MCP and PIPs joints are affected as well as the wrists. But DIP joints are not