3: MRI 2 Flashcards

1
Q

What forces control ion movement in neuron cells

A

electrical & concentrational:

  • positive charge is attracted to negative environment (Na+ flows into the negative cell)
  • Potassium diffuses across the membrane (Then more Na+ is moved outside and less K+ inside)

)

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2
Q

What is Na+

A

Sodium

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3
Q

What is K+

A

Potassium

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4
Q

What is the resting potential of a neuron? (neuron at rest)

A

~ -70/65mV (concentration of ions is kept constant through Na+/K+ pumps)

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5
Q

What is the action potential threshold of a neuron?

A

~ -55mV (Once threshold is reached, the Na+ voltage gated channels are opened, the potassium channel is slower)

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6
Q

What are the ‘nodes of ranvier’?

A

periodic gap in the insulating sheath (myelin) on the axon of certain neurons that serves to facilitate the rapid conduction of nerve impulses

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7
Q

How are neurotransmitters removed from synapses?

A
  • Reuptake

- Enzymes break them down and recycle

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8
Q

What are IPSP and EPSP

A

IPSP - inhibitory postsynaptic potential

EPSP - excitatory postsynaptic potential

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9
Q

What % of neuronal energy do POSTSYNAPTIC POTENTIALS consume?

A

37.5%

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10
Q

What % of neuronal energy do ACTION POTENTIALS consume?

A

15.8%

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11
Q

What % of neuronal energy do RESTING POTENTIALS consume?

A

15%

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12
Q

What % of neuronal energy does PRESYNAPTIC TRANSMITTER RELEASE consume?

A

3.8%

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13
Q

What % of neuronal energy does TRANSMITTER RECYCLING consume?

A

3%

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14
Q

What % of neuronal energy does HOUSEKEEPING consume?

A

25%

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15
Q

How do PET scans work?

A
  • Create radioactive glucose and inject it
  • increased bloodflow results in increased concentration of the radioactive substance in a brain region
  • A positron is shot at and clashes with an electron and releases gamma rays in two directions (each time a random direction - sum of them allows to zero in on where the rays come from)
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16
Q

What are the magnetic properties of haemoglobin and their effects on T2 decay?

A
  • Deoxygenated haemoglobin reduces magnetic signal

T2:
- Deoxy haem = relax quicker

  • Oxy haem = in synch longer
17
Q

fMRI relies on the fact that deoxygenated haemoglobin disrupts…

A

the homogeneity of the magnetic field

18
Q

EPSPs cause a neuron to become

A

depolarized

19
Q

When do voltage-gated sodium ion channels open?

A

At the onset of an action potential

20
Q

the influx of ____ is critical for neurotransmitter release

A

calcium