3 - Male Reproductive Histology Flashcards
What are the primary and secondary sex organs?
Primary = Gonads = Testes; sperm cells and hormones
Secondary = Storage, Survival, Conveyance of Sperm
What is the site of sperm production?
What are the intratesticular genital ducts?
What are the extratesticular genital ducts?
What are the Acessory glands?
- What is the site of sperm production
- Semiminferous Tubules
- Intratesticular genital ducts
- Tubuli Recti
- Rete Testis
- Efferent Ductules
- Extratesticular Genital Ducts
- Epididymis
- Ductus Deferens
- Ejaculatory Duct
- Urethra
- Accessory Glands
- Seminal Vesicles
- Prostate
- Bulbourethral Glands
What is the path of sperm production, modification, and ejaculation?
- Testis
- Epididymis
- Ductus Deferens
- Seminal Vesicle
- Prostate
- Bulbourethral Glands
- Urethra
SPERM DURING EJACULATION: SEVEN UP
Seminiferous Tubules
Epididymis
Vas Deferens
Ejaculatory Udcy
Nothing
Urethra
Penis
What coveres the testis?
What forms the septa that organize the seminiferous tubules into lobules?
Testes are covered by tunica albuginea
Tunica Albuginea invaginates to form septa that organize the seminiferous tubules into lobules
Where does sperm formation occur?
What cells populate the lining epithelium of seminiferous tubules?
What cells are located between the seminiferous tubules?
Spermatogenesis occurs in the seminiferous tubules
- Sertoli Cells support, nourish, and regulate the activity of spermatogenic cells; forms Blood Testes Barrier (BTB)
-
Spermatogenic Cells in various stages of development
- - -
Interstitial Cells (Endocrine Leydig) produce and secrete testosterone; controls development of spermatozoa within the tubule; occurs continuously through life
What is the role of Sertoli Cells?
What controls the rate of spermatozoa formation?
What is the pathwat for intratesticular ducts?
Secrete growth factors/nutrients, waste removal, secrete inhibin (prevent auto-immune action against sperm)
Testosterone controls the rate of sperm formation
Seminiferous Tubules - Tubuli Recti - Rete Testes - Efferent Ducts
Once spermatogenic progenitor cells undergo mitosis to produce what?
Upon completion Meiosis I, what is formed?
Upon completion of Meiosis II, what is formed?
Primary Spermatocytes
Two haploid Secondary Spermatocytes
Four haploid Spermatids

Seminiferous Tubules

Seminiferous tubule dark black line
Dotted line is Leydig Cell–secrete testosterone, b/t tubules
What cells is shown within tubule, arrow off screen?

Sertoli Cell
What short, straight ducts do spermatozoa produced in seminiferous tubules pass through?
What do these connect to?
Tubuli Recti
Rete Testis

S = Seminiferous Tubules
T = Tubuli Recti
R = Rete Testis , lined by cuboidal epithelium

ST = Seminiferous Tubules; with S - Septa in between
Tubuli Recti leading to Rete Testes
What connects the rete testis to the head of the epididymis?
Efferent Ductules connect the rete testis to the head of the epididymis
Absorb extra fluid from seminiferous tubules
Non-ciliated cuboidal epithelium, “scalloped appearance”


Efferent Ductules
Note scalloped appearance

Where is sperm ejaculated from?
Epididymis

Epididymis
Note smooth muscle, columnar cells on closeup

Epididymis
What forms the ejaculatory duct?
Ampulla of Ductus Deferens (Vas Deferens)
+
Duct of Seminal Vesicle
What is the path of sperm after the efferent ductules?
Epididymis
Ductus Deference
Ejaculatory Duct
Urethra (Prostatic - Membranous - Penile Portion)

Ductus Deferens
Inner - Longitudinal Smooth Muscle
Middle - Circular Smooth Muscle
Outer - Longitudinal Smooth Muscle

Ductus (vas) Deferens
What is the purpose of the seminal vesicles?
Secretes fructose for energy for sperm
Secrete prostaglandins
Secrete fibrinogen so make semen sticky

Seminal Vesicle
Secretes fluid with sperm before ejaculatory duct

Seminal Vesicle

Prostate Gland
Note Cirps Amylaceum Concretion

Prostate
Note Prostatic Concretion
What is the purpose of the urethral glands?
Secrete alkaline mucoid solution into lumen to lubrican for ejaculate and neutralize uric acid left in tract after urination
What surrounds the two cylinders of curpora cavernosa?
What is purpose of corpus spongiosum?
Thick tunica albuginea
Rigid, permits erection
No Tunica albuginea, spongy urethra courses through here
Does not become rigid during erection, must allow ejaculate to expel

Upper 2/3 = Corpus Cavernosa
Lower 1/3 = Corpora Cavernosa