3 GAs Flashcards
1
Q
there’s a strong correlation between anaesthetic potency and
A
its solubility in olive oil
2
Q
how do GAs work
A
bind to a hydrophobic pocket in >1 target proteins
3
Q
what do GAs target
A
GABA A receptors, specifically beta subunits (if volatile, alpha and beta)
4
Q
how do GAs act at NMDA receptors
A
compete for binding w glycine (essential co agonist)
