3 Encephalopathy and Seizures: Diagnosis and Managment Flashcards

1
Q

What is the forebrain comprised of

A

Cerebrum and diencephalon

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2
Q

Main indicator that something is wrong with animal’s forebrain

A

personality change

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3
Q

Unique symptoms of change in the forebrain

A

Blindness
Seizures
Circling

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4
Q

Definition of encephalopathy

A

Brain dysfunction

Non-specific

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5
Q

Extra cranial liver causes of encephalopathy

A

portosystemic shunt

liver failure

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6
Q

Signalment for portosystemic shunt encephalopathy

A

Little young dog

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7
Q

Other causes of extracranial causes of encephalopathy

A

Toxins
Insulinoma causing hypoglycemia and seizures
Vascular

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8
Q

Intercranial causes of encephalopathy

A

Neoplastic
Inflammatory disease
Trauma
Less likely - infectious

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9
Q

Head pressing usually neurolocalizes to

A

Forebrain

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10
Q

What tests do you run if you’re worried a dog has cirrhosis

A

Bile acids

Ammonia

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11
Q

What will an ammonia test tell you

A

If normal will not rule out liver disease

Will tell you if current dysfunction is due to the liver.

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12
Q

What would cause an increased ammonia with strange behavior

A

Hepatic encephalopathy

if normal ammonia, not a rule out

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13
Q

Purpose of imaging a dog with suspected hepatic encephalopathy

A

Look for shunts

Size of liver

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14
Q

What test do you do to determine condition of the liver

A

Biopsy

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15
Q

Initial treatment for a dog with suspected hepatic encephalopathy

A

Lactulose, denamerian, low protein diet, +/- antibiotic (for gut flora, metronidazole)

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16
Q

Do you treat patients that are having seizure due to hepatic encephalopathy

A

Not usually

treat underlying disease

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17
Q

Best way to diagnose hydrocephalus

A

Ultrasound the head

Black fluid all around brain

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18
Q

Characteristics of congenital hydrocephalus

A

Malformation of the ventricular system
Irreversible
Can prevent deterioration

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19
Q

Main cause of acquired hydrcephalus

A

tumor

Inflammatory diseases

20
Q

Treatment for hydrocephalus

A

Reduce CSF production

21
Q

Medications that reduce CSF production

A

Omeprazole
Prednisone - antiinflammatory dose
Acetazolamide - dont use commonly, will mess with renal function

22
Q

What can you do if medical managment fails to reduce CSF production

A

Place a shunt

23
Q

Emergency treatment to reduce CSF production

A

Mannitol

Hypertonic saline

24
Q

Seizure classifications

A

Generalized
Partial
Psychomotor

25
Types of generalized seizures
Grand mal | Tonic-clonic
26
Partial seizures
Focal motor seizures | Jacksonian march
27
Psychomotor seizures
Fly biting running fits RAAMMPPAAGGGEEE (rage)
28
Petit mal characteristics
Mild generalized seizure Brief loss of muscle tone Ataxic Episodic weakness
29
What type of seizure has sensory and motor components, is a complex partial seizure, or a behavioral seizure. Usually comes from the temporal lobe and limbic system. Emotion
psychomotor seizure
30
Cluster seizures
> 2 seizures in 24 hours Normalcy in between episodes Reliable pattern Require multiple medications
31
Status epilepticus
Rapidly recurring seizures with incomplete recovery between episodes
32
Characteristics of status epilepticus
``` large breed dogs Toxins Metabolic Sudden drug withdrawal Progressive disease ```
33
Tumors that may cause seizures
``` Nasal tumor HSA Melanoma - metastasize LSA OSA ```
34
Shunt breeds
Pug Yorkie Pom
35
Vascular breeds
King Charles Greyhound Cats
36
Differentials for intracranial vascular seizures
Ischemic vs hemorrhagic infarction Thromboembolus Hemorrhage
37
Differentials for intracranial infectious seizures
Crypto, rabies Distemper Toxo, FIP
38
Differentials for intracranial anomalous seizures
hydrocephalus | Lissencephaly
39
Differentials for intracranial traumatic seizures
Acute | Chronic
40
Differentials for intracranial degenerative seizures
Storage disorders
41
Differentials for intracranial inflammatory seizures
GME NME NLE (small dogs)
42
Young dog with extra cranial
PSS, BG, toxin
43
Young dog with intracranial DDx
Malformation, storage disease, infectious (distemper vs sepsis) IE
44
Middle age dog DDx
IE, inflammatory, infectious, neoplasia
45
Old dog DDx
Neoplasia, inflammatory, IE, Vascular