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OrganHisto Exam 1 > 3. Dom Lahey > Flashcards

3. Dom Lahey Flashcards

1
Q

What is the general function of the immune system?

A

storage of lymphocytes, increase number of lymphocytes, provide favorable environment for establishing immunity

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2
Q

Surface protection, acute inflammation, compliment process, lysosome production, and natural barriers describe what type of immunity?

A

innate

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3
Q

Humoral and Cell-Mediated are 2 examples of what type of immunity?

A

aquired (adaptive)

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4
Q

Response to invading bacteria, mediated by B cells/plasma cells, and involves antibody production is which form of adaptive immunity?

A

humoral

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5
Q

Usually response to virus, fungi, foreign cells, mediated by T lymphocytes, does NOT depend on B lymphocyte participation, and cytotoxic response is which type of adaptive immunity?

A

cell mediated

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6
Q

No/incomplete capsule, humoral immunity describes what?

A

diffuse lymphatics

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7
Q

Gastrointestinal, respiratory, urogenital tracts…secretory IgA = secreted on to free epithelial surfaces (tears, saliva, gut lumen, nasal, vaginal)
- FIRST line of defense against infection (antigen specific)…what is this?

A

MALT

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8
Q

Gastrointestinal tract (individual lymph nodules, Peyer’s patches)…is what?

A

GALT

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9
Q

Respiratory lymph nodules, form when air tubes bifurcate…is what?

A

BALT

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10
Q

Roof of nasopharynx, called Adenoids when inflamed, can cause ear-infection describes which form of tonsils?

A

pharyngeal tonsils

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11
Q

Surface epithelium in the pharyngeal tonsil are what type of cells?

A

respiratory epithelium

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12
Q

Boundary of oral cavity/oropharynx, partial capsule likely describes what type of tonsils?

A

Palatine Tonsils (Tonsilar Crypts)

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13
Q

Surface epithelium in the palatine tonsils are what type of cells?

A

stratified squamous

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14
Q

Advantages and disadvantages of the palatine tonsils are what?

A

advantages - more SA for detecting foreign antigens and lymph node formation

disadvantages - deep depressions (bacteria can thrive = infection = tonsillitis)

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15
Q

The tonsil that is on the dorsal posterior 1/3 of tongue (oral cavity) is what?

A

Lingual Tonsils (Tonsilar Crypts)

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16
Q

Surface epithelium in the lingual tonsils are what type of cells?

A

stratified squamous

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17
Q

The tonsillar ring around openings to digestive/respiratory system is referred to as what?

A

Waldeyer’s Ring

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18
Q

Which organs have a capsule, both humoral and cell-mediated immunity?

A

lymphatic organs

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19
Q

Which type of lymphoid organs provide environment where lymphocytes become immunocompetent (thymus and bone marrow)?

A

primary

20
Q

Which type of lymphoid organs provide an environment where lymphocytes can contact foreign antigens and interact with each other (spleen and lymph nodes)?

A

secondary

21
Q

What is the function of the lymph nodes?

A

filtration of lymph using phagocytosis, establish humoral/CM immunity

22
Q

Which lymph node structure is described…dense irregular CT of moderate thickness (trabecular)?

A

capsule (septa)

23
Q

Which lymph node structure is described…in-coming vessels, contain valves?

A

afferent lymphatics

24
Q

Which lymph node structure is described… out-going vessels, contain valves?

A

efferent lymphatics

25
Q

Which lymph node structure is described…recessed area where efferent lymph exits, blood enters/exits?

A

Hilum

26
Q

Marginal sinus and the first to receive afferent lymph is what type of sinus?

A

Subcapsular sinus

27
Q

Which type of sinus passes thru the cortex region?

A

Cortical sinus

28
Q

Which type of sinus passes thru the deep cortex/paracortex region?

A

Deep cortical sinus

29
Q

Which type of sinus passes thru the medulla region?

A

Medullary sinus

30
Q

Regions and cells of a lymph nod, within ALL regions/sinuses are supported by system of what type of fibers and cells?

A

reticular fibers produced by reticular cells

31
Q
  • Primary cell type = B lymphocyte
  • Activity = phagocytosis and humoral immunity (primarily IgG)

This describes which part of the lymph node?

A

cortex

32
Q

AKA thymus dependent zone AKA deep cortex

  • Primary cell type = T lymphocyte
  • Activity = phagocytosis, cell-mediated immunity (long-term storage T cells)

This describes which part of the lymph node?

A

paracortex

33
Q

Primary cell type = Plasma cells
Activity = phagocytosis, some cell-mediated immunity
* mostly humoral immunity because of ANTIBODY secretion

This describes which part of the lymph node?

A

medulla

34
Q

Which structure has 2 lobes extending over the great heart vessels, primary lymphoid organ, involution starts after puberty?

A

thymus

35
Q

What organ’s function is to establishment of immunocompetent T lymphocytes? It can distinguish self from non-self antigens to develop self tolerance.

A

thymus

36
Q

T lymphoblast in the thymus is called what?

A

thymocyte

37
Q

contains high cell concentration, large # of T lymphatics and macrophages, TEC types 1,2,3
* support using cytoplasmic processes, important blood-thymic barrier

This describes which part of the thymus?

A

cortex

38
Q

contains lower cell density, fewer but larger T cells, macrophages, APC (dentritic cells), TEC types 4,5,6
* form thymic corpuscles

This describes which part of the thymus?

A

medulla

39
Q

What cells are produced in bone marrow, enter thymus as immonincompetent cells, and then leaves bloodstream at corticomedullary line?

A

T Lymphocytes

40
Q

What area of Spleen has areas of concentrated WBCs, primarily lymphocytes?

A

white pulp

41
Q

What is the function and area of the Spleen that the white pulp is located?

A 
Function = immunity
Areas = next to capsule and setpa, splenic nodules, periarteriolar lymphoid sheaths (surround central arteries, cell-mediated)
42
Q

What is the area of the Spleen that is not white pulp or CT (most of spleen is RED)

A

red pulp

43
Q

What is the function of the red pulp of the spleen?

A

rapid blood filtration, contact with blood-born foreign antigens

44
Q

Caused by Epstein-Barr virus (EBV) in mucus/saliva. First replicates in nasopharyngeal epithelium, Can spread to salivary glands, lymph nodes and oropharyngeal lymphoid tissues, Then to liver, spleen, B cells, and blood. What diseases does this describe?

A

infectious mononucleosis

45
Q

Blood changes: increase in number of platelets and abnormal RBC’s and
Infection: Increased risk of bacterial septicemia especially in children with Strep Pneumo

These condition typically lead to what?

A

splenectomy

OrganHisto Exam 1 (3 decks)

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