3. Clinical Endocrine

Question 1

Differentiate between men and women symptoms of prolactinoma

Answer 1

Men - impotence, loss of libido, visual problems, headache)

Women- oligomennorrhea, amenorrhea, galactorrea, infertility

Question 2

What two kinds of drugs increase prolactin levels?

Answer 2

Antidepressants and antipsychotics

Question 3

What is the most common hormone secreting tumor

Answer 3

Prolactinoma

Question 4

Prolactinomas can be classified based on when it is discovered. Postpartum, not post-partum

Answer 4

Post-partum: Chiari-frommel syndrome

Not pp: deal castilos syndrome

Question 5

What is the optimal tx for prolactinoma?

Answer 5

Cabergoline - more effective and less side effects but more expensive

Question 6

GH causes an increase in what?

Answer 6

IGF-1

Question 7

What is the mean age of acromegaly?

Answer 7

Third decade of life (mean age is 42 y/o)

Delay of symptom onset to dx is 8yrs

Question 8

Tx of acromegaly

Answer 8

Surgery, bromocriptine

Question 9

Clinical features of acromegaly

Answer 9

Enlarged hands, feet, course facial features, headaches, CHF, parasthesis, joint pain, WIDELY SPACED TEETH, OSA, HTN/cardiomegaly, OA

Question 10

Where do pituitary tumors metastasize?

Answer 10

Breast and lung