[3] Anti-Parasitics

Question 1

[Drug of Choice]

Ascaris

Answer 1

Albendazole

Question 2

[Drug of Choice]

Hookworms

Answer 2

Albendazole

Question 3

[Drug of Choice]

Capillaria

Answer 3

Albendazole

Question 4

[Drug of Choice]

Filaria

Answer 4

Diethylcarbamazine

Question 5

[Drug of Choice]

Schistosoma

Answer 5

Praziquantel

Question 6

[Drug of Choice]

T. saginata

Answer 6

Praziquantel

Question 7

[Drug of Choice]

A. lumbricoides

Answer 7

Albendazole / Mebendazole

Question 8

[Drug of Choice]

Ancylostoma duodenale

Answer 8

Albendazole

Question 9

[Drug of Choice]

T. trichiura

Answer 9

Albendazole / Mebendazole

Question 10

[Drug of Choice]

Strongyloides stercoralis

Answer 10

Ivermectin

Question 11

[Drug of Choice]

Enterobius vermicularis

Answer 11

Albendazole / Mebendazole

Question 12

[Drug of Choice]

Capillaria philippinensis

Answer 12

Albendazole

Question 13

[Drug of Choice]

Cysticercosis

Answer 13

Albendazole

Question 14

[Drug of Choice]

Diphyllobotrium latum

Answer 14

Praziquantel

Question 15

[Drug of Choice]

Echinococcus granulosis

Answer 15

Albendazole

Question 16

[Drug of Choice]

Paragonimus westermani

Answer 16

Praziquantel

Question 17

Best anti-helminthic drug and usual drug of choice due to its broad spectrum

Answer 17

Albendazole

Question 18

Drug used for severe amoebiasis

Answer 18

Metronidazole

Question 19

Describe metronidazole’s drug interaction with alcohol

Answer 19

Disulfiram-like reaction, a drug that produces acute sensitivity to alcohol

Question 20

Most common organism causing Malaria

Answer 20

Plasmodium falciparum

Question 21

Only tissue schizonticide for Malaria

Answer 21

Primaquine

Question 22

Treatment Regimen for Uncomplicated Vivax Malaria

Answer 22

Day 0 and 1: Chloroquine

• 150 mg base tablet
• 10 mg/kg/day
• 4 tablets a day

Day 2: Chloroquine

• 150 mg base tablet
• 5 mg/kg/day
• 2 tablets a day

Day 3 to 17: Primaquine

• 15 mg base tablet
• 0.5 mg/kg/day
• 1 tablet a day

Question 23

First line drug for Malaria

Answer 23

Artemether-Lumefantrine (Coartem)

Question 24

Toxic effect of Quinine

Answer 24

Cinchonism:

• GIT Distress
• Headache
• Vertigo
• Blurred vision
• Tinnitus

Question 25

Drug used for P. vivax infection

Answer 25

Chloroquine

Question 26

[Mechanism of Action] Chloroquine

Answer 26

Prevents biocrystallization of parasitic heme into hemozoin causing heme buildup and lysis of parasite