[3] Anti-Parasitics Flashcards

1
Q

[Drug of Choice]

Ascaris

A

Albendazole

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2
Q

[Drug of Choice]

Hookworms

A

Albendazole

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3
Q

[Drug of Choice]

Capillaria

A

Albendazole

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4
Q

[Drug of Choice]

Filaria

A

Diethylcarbamazine

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5
Q

[Drug of Choice]

Schistosoma

A

Praziquantel

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6
Q

[Drug of Choice]

T. saginata

A

Praziquantel

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7
Q

[Drug of Choice]

A. lumbricoides

A

Albendazole / Mebendazole

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8
Q

[Drug of Choice]

Ancylostoma duodenale

A

Albendazole

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9
Q

[Drug of Choice]

T. trichiura

A

Albendazole / Mebendazole

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10
Q

[Drug of Choice]

Strongyloides stercoralis

A

Ivermectin

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11
Q

[Drug of Choice]

Enterobius vermicularis

A

Albendazole / Mebendazole

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12
Q

[Drug of Choice]

Capillaria philippinensis

A

Albendazole

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13
Q

[Drug of Choice]

Cysticercosis

A

Albendazole

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14
Q

[Drug of Choice]

Diphyllobotrium latum

A

Praziquantel

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15
Q

[Drug of Choice]

Echinococcus granulosis

A

Albendazole

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16
Q

[Drug of Choice]

Paragonimus westermani

A

Praziquantel

17
Q

Best anti-helminthic drug and usual drug of choice due to its broad spectrum

A

Albendazole

18
Q

Drug used for severe amoebiasis

A

Metronidazole

19
Q

Describe metronidazole’s drug interaction with alcohol

A

Disulfiram-like reaction, a drug that produces acute sensitivity to alcohol

20
Q

Most common organism causing Malaria

A

Plasmodium falciparum

21
Q

Only tissue schizonticide for Malaria

A

Primaquine

22
Q

Treatment Regimen for Uncomplicated Vivax Malaria

A

Day 0 and 1: Chloroquine

  • 150 mg base tablet
  • 10 mg/kg/day
  • 4 tablets a day

Day 2: Chloroquine

  • 150 mg base tablet
  • 5 mg/kg/day
  • 2 tablets a day

Day 3 to 17: Primaquine

  • 15 mg base tablet
  • 0.5 mg/kg/day
  • 1 tablet a day
23
Q

First line drug for Malaria

A

Artemether-Lumefantrine (Coartem)

24
Q

Toxic effect of Quinine

A

Cinchonism:

  • GIT Distress
  • Headache
  • Vertigo
  • Blurred vision
  • Tinnitus
25
Q

Drug used for P. vivax infection

A

Chloroquine

26
Q

[Mechanism of Action]

Chloroquine

A

Prevents biocrystallization of parasitic heme into hemozoin causing heme buildup and lysis of parasite