3: Antenatal care and screening in pregnancy Flashcards

(40 cards)

1
Q

When are the first, second and third trimesters?

A

1st trimester - 1 to 12 weeks

2nd trimester - 13 to 28 weeks

3rd trimester - 29 to 40 weeks

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2
Q

When is antenatal care given?

A

Before birth

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3
Q

What is the sensitivity of a test?

A

Proportion of people with a disease which are detected by the test

i.e test positives / (test positives + false negatives)

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4
Q

What is the specificity of a test?

A

Proportion of patients without a disease who are identified by a test

i.e true negatives / (true negatives + false positives)

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5
Q

How is sensitivity calculated?

A

Sensitivity = (True positives) / (True positives + False negatives)

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6
Q

How is specificity calculated?

A

Specificity = (True negatives) / (True negatives + False positives)

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7
Q

What is the positive / negative predictive value of a test?

A

Proportion of positives/negatives who are actually true

e.g PPV = (True positives) / (True positives + False positives)

gives you an idea of how reliable a test is

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8
Q

Screening tests tend to be used to rule diseases ___.

A

rule diseases out

wide variety of diseases can be screened for, then if any of them are positive, a diagnostic test can be performed

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9
Q

When are ultrasound scans carried out in pregnancy?

A

12 weeks

20 weeks - more detailed one

To test for structural abnormalities e.g those seen in Down’s syndrome

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10
Q

What is Naegele’s rule for calculating a woman’s due date?

A

Take date of last period

Add on nine months and seven days i.e 280 days

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11
Q

What are some early blood tests done in antenatal care?

A

Hb - for sickle cell anaemia anaemia

Blood group

Rhesus antibodies

STIs - syphilis, HIV, Hepatitis B & C

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12
Q

What are the steps of antenatal abdominal examination?

A

Inspect

Palpate - fundus, fundal height, walls for foetal lie and presentation, ballot the presenting part

Auscultate - foetal heart

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13
Q

What vital signs and tests are routine at antenatal appointments?

A

HR, BP, BMI

BG

Urinalysis

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14
Q

What is the difference between the lie and presentation of a foetus?

A

Lie - baby’s position in the womb i.e longitudinal or transverse

Presentation - what part of the baby is most inferior i.e cephalic (head) or breech (feet)

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15
Q

What is a normal foetal heart rate?

A

120 - 160 bpm

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16
Q

How is fundal height measured?

A

Fundus of uterus to Pubic symphysis

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17
Q

What is the purpose of antenatal ultrasound testing?

A

To assess the structure of a foetus for abnormalities and treat them where possible

18
Q

What is placenta praevia?

A

Placenta lies low in the uterus, obstructing the opening of the cervix

19
Q

How can placenta praevia be detected?

What are the symptoms?

A

Ultrasound scan

Bleeding

20
Q

Which genetic disorder is screened for in all pregnant women?

A

Down’s syndrome

21
Q

What should couples be asked before screening for Down’s syndrome is carried out?

A

Are you sure you want to know?

Have you considered what you would do if positive (i.e keep the baby or termination)?

22
Q

If a baby having Down’s syndrome would make no difference to their parents, should the mother have a screening test?

A

Arguably no, it makes no difference

23
Q

How does maternal age influence the risk of trisomy 21?

A

As maternal age increases, risk of trisomy 21 increases

24
Q

Which measurement on foetal ultrasound is used to estimate gestational age?

A

Crown-rump length

25
Which **measurement** on foetal ultrasound is used as a predictor for Down's syndrome?
**Nuchal thickness / frequency** (NT or NF)
26
What is a **normal value** for **nuchal thickness**?
**\< 3.5 mm**
27
A **nuchal thickness** \> ___ mm is suggestive of **Down's syndrome.**
**\> 3.5 mm**
28
Which **serology** **tests** can be used along with **maternal age** and **nuchal thickness** to calculate the risk of Down's syndrome?
**HCG** (will be increased) **AFP** (will be reduced) **PAPP-A** (will be reduced)
29
Apart from **ultrasound** and **serology**, what sampling tests can be used to diagnose genetic disorders? From what point in gestation can they be done?
**NIPT** (non-invasive prenatal testing) from **8 weeks** **Chorionic villus sampling** from **12 weeks** **Amniocentesis** from **16 weeks**
30
What is the **risk** carried alongside **chorionic villus sampling** and **amniocentesis**?
**Miscarriage** Tiny percentage but still a risk
31
What are **two haemoglobin disorders** which are tested for in antenatal care?
**Sickle cell anaemia** **Thalassaemia**
32
Although it is important to screen for anaemia in babies, who else might develop it before or after pregnancy?
**The mother**
33
Which disease, involving **antibodies**, can cause **anaemia** and **jaundice** in a baby?
**Rhesus disease**
34
Which **psychiatric disorders** should be screened for in antenatal care?
**Post-partum depression** **Post-partum psychosis**
35
Which **endocrine disease** should be screened for in antenatal care?
**Gestational diabetes**
36
What are the risks to a baby following birth if the mother has untreated **gestational diabetes**?
**Macrosomia** OR **Small-for-dates** ## Footnote **Hypoglycaemia** **Stillbirth**
37
How can **foetal growth** be assessed?
**Measurement of fundal height** **Ultrasound scanning**
38
If a woman is thought to be at risk of **pre-eclampsia**, what drug are they asked to take?
**75mg aspirin** Daily from 12 weeks until birth
39
Why are pregnant women routinely given a **urinalysis**?
To detect: **UTI** **Asymptomatic bacteruria** (which is treated with antibiotics in pregnant women) **Diabetes**
40
Why is **asymptomatic bacteruria** treated in pregnant women?
**30-40% go on to develop a UTI**