3 Flashcards
lipolysis
breakdown of lipids into glycerol and fatty acids
what stimulates/increases lipolysis
glucagon and inhibitation of insulin increases lyopsisis
catabolism vs anabolism
Anabolism molecules join together whilst storing energy. Catabolism is the breakdown of molecules to release energy
vasopressin/ADH
decreases water excretion by the kidneys by increasing water reabsorption in the collecting ducts ulimtaltey increasing urine production
diabetes insipidus is caused by
a lack of ADH, too much urine
what is an automimmune disease
when the immune system relases antiobodies that attack self cells usuaulyl because these antibodies do not recognise self cells to mulfunction
an example is when self cells do not contain antigen or when antiobodies do not recognise antigen.
Why does type 1 diabetes cause one to be lethargic
not enough insulin is beign absorbed by the body, thus glucose cannot enter our cells which prevnts cells from reciveiieng the energy they need thus causing us to become tired and lethargic
how does mellitus lead to hyperglycaemia
- in diabetes melltius, there is the production of autoantibodies which destroy beta cells and thus, there is a lack of insulin production OR there is insulin resistance
- in both cases, glucose is not absorbed or stored as glycogen in the tissues as insulin is the hormone that is responsible for that
- therefore there will be increased levels of glucose in the bloodstream caysing hyerpglycemia
main reason for type 2 diabetes
- insulin resistance
what is insulin resistance
when cells is skeletla muscles liver and fat do not respond to insulin
what cells/tissues are affected throughout type 2 diabetes
liver tissue, skeletal muscle, fat tissue are all affected in type 2 diabetes
Why does diabetes cause frequent urination and thirst and what role does homeostasis play in this
- In diabetes there is increassed concentration of glucose in the bloodstream
2.Sometimes this leads to access glucosse in the urine(glucosuria)
- Thus water secretion into the tubules increases leading to increasing urination
- In addition, as there is increased urination, this will send signals to the hypothalamus that there is decreased blood volume through osmoreceptors and baroreceptors.
5.iN order to correct the blood volume back to homeostatic levels, the hypothalamus increases thirst
why does diluted urine in daibetes and what role does hoemtositias play
access amounts of glucose results in more glucose ending up in tubulues es reusltingin more and more wtaer being secreted into the bladder htrough the tubules ulitmaltey causing water becomes diulted
why does freuqnety urination ocucr in diabebte termsof osmolarity
sacess glucose that goes htoruhg the tubules which causes water to follow the soultes because of the water is hypertonic to the glucose causing water to exit the tubules more frequently, thus resulting in frequent urination.
why is thirst and frequent urination assocaited with hyerpgmyalceimia and type 2 diabetes
- As there is increased urination due to hyperglycemia, this will cause a decrease in the blood volume.
- The decrease in blood pressure is detected by baroreceptors and the decrease in blood volume is detected by osmoreceptors.
3.These signals are sent to the hypothalamus and the hypothalamus sends a signal to increase thirst in order to allow the human to consume more water as a way to increase blood volume levels