2nd Midterm Exam Flashcards
Motor unit:
where neurons (alpha motor neurons) activate muscles
Lateral corticospinal tract:
Control of fine motor movement, Acts on more distal limbs→ Also pyramidal tract. A bundle of axons that originate in the cortex and terminate mono-synaptically on alpha motor neurons and spinal interneurons in the spinal cord. Many of these fibers originate in the primary motor cortex, although some come from secondary motor areas. The corticospinal tract is important for the control of voluntary movements.
Medial tract:
Controls walking, posture, standing, Acts on more proximal parts of limbs and the trunk
Vestibulocerebellum:
balance, eye movement
Spinocerebellum:
smooth control of movement, coordination in walking
Cerebrocerebellum:
highly skilled movements requiring sensorimotor learning
Ataxia:
Damage to the cerebellum from stroke, tumor, or degenerative processes results in a syndrome known as ataxia. Patients with ataxia have difficulty maintaining balance and producing well- coordinated movements.
Nigrostriatal system (substantia nigra) of the basal ganglia
Movement
The basal ganglia play a critical role in
movement initiation
The substantia nigra (in basal ganglia) excites the direct pathway by
acting on one type of dopamine receptor (D1) and inhibits the indirect pathway by acting on a different type of dopamine receptor (D2).
What is a motor plan? Which brain regions are involved in forming a motor plan?
-Supplementary & Premotor areas
-Motor plan: representation of intended movement
•General information about the goal of the movements
•Specific information about the muscular control needed
Mirror neurons:
Responds to not only doing actions, but also to someone else doing the same action. Can be very specific or also more broad (slides)
-Mirror neurons: A neuron that shows similar responses when an animal is either performing an action or observing that action produced by another organism.
What is the role of the ACC in control of actions?
Anterior cingulate cortex (ACC):
•Debated role in various functions, including motor, attentional, and emotional
•Control and planning of movements
•Novel, untrained movements
•Selecting for movement among competing alternatives
•Error detection
Primary Motor Cortex (M1)
- Organization around specific attribute of physical world
- Specific body area controlled by specific motor region
- Distortion relative to physical world
- Parts of body with fine motor control are bigger
- Mapping is upside down
- Body parts represented inversely on cortex
Recall damage to parietal regions (dorso-dorsal stream) causes
optic ataxia
Corticomotor neurons:
neurons that synapse directly onto alpha motor neurons instead of onto spinal interneurons
Neuroprosthetics take advantage of the _____to interface with machines in lieu of limbs
cortex’s patterns of activity in planning motor movements
Apraxia:
A neurological syndrome characterized by loss of skilled or purposeful movement that cannot be attributed to weakness or an inability to innervate the muscles. Apraxia results from lesions of the cerebral cortex, usually in the left hemisphere. Difficulty pronouncing words.
-Apraxia is a disorder in which the patient has difficulty producing coordinated, goal-directed movement, despite having normal strength and control of the individual effectors
What are brain-machine interfaces?
brain–machine interfaces (BMIs), use decoding algorithms to control prosthetic devices with neural signals.
For instance, could you plan an action in your motor cortex (e.g., let’s fold the laundry), somehow connect those motor cortex neurons to a computer, and send the planned action to a robot, which would fold the laundry
What is a limitation that BMI face in being more like human motor systems?
A major limitation with most BMI systems is that they operate in an “open-loop” mode, providing motor commands to prosthetic devices but not taking advantage of sensory feedback.
3 General Neural Networks in Attention:
- Alerting: maintaining sensitivity to incoming info (noradrenaline)
- Orienting: aligning attention with sensory input (acetylcholine)→ selective att.
- Executive: modulating attentional activity (dopamine)
-Arousal and attention role: norepinephrine
Selective attention:
processing relevant information while ignoring irrelevant information
Top-down control (goal-driven control):
steered by an individual’s current behavioral goals and shaped by learned priorities based on personal experience and evolutionary adaptations→ Knowledge, expectations, goals drive allocation of attention
Bottom-up control (stimulus-driven control):
Your reaction is stimulus-driven which is much less dependent on current behavioral goals→ Sensory input captures attention allocation
The mechanisms that determine where and on what our attention is focused are referred to as ___ and they involve widespread but highly specific cortical and subcortical networks that interact so that we can selectively process information
attentional control mechanisms
Overt (obvious) attention:
focusing and perceiving what eyes are fixated on→ eye gaze direction