2B haem

Question 1

[Classical HL - Favorable criteria

Answer 1

BEEN
B - bulky
E - extranodal disease
E - ESR >50 (no B-Sx) or >30 (with B-sx)
N - ≥3 nodal areas

Question 2

Classical HL
Favourable disease - stage 1-2A

Answer 2

2x ABVD + 20/10
If female - consider 3x ABVD then repeat PET
If negative, no further treatment
If positive, 4th ABVD then 30/15

Question 3

Classical HL
Unfavourable disease - stage 1-2A

Answer 3

4x ABVD + 30/15 or 6x ABVD

Question 4

Classical HL
Advanced disease - 2B and beyond

Answer 4

2x ABVD then repeat PET
If negative -> 4x AVD
If positive -> esc Beacopp chemo then PET
If still positive - salvage Pt-based chemo or RT

Question 5

Nodular lymphocyte predominant HL
Stage 1A-2A (2 sites only)

Answer 5

30/15 IFRT

Question 6

Nodular lymphocyte predominant HL
Stage 2A (3 sites or more)

Answer 6

2x ABVD + 20/10

Question 7

Nodular lymphocyte predominant HL
Bulky disease

Answer 7

4x ABVD + 30/15

Question 8

Nodular lymphocyte predominant HL
Stage 3-4

Answer 8

6x ABVD

Question 9

DLBCL
Stage 1-2A, non-bulky

Answer 9

3x R-CHOP & 30/15

Question 10

DLBCL
Stage 2B-4, +/- extranodal site

Answer 10

6x R-CHOP

Question 11

DLBCL
Stage 4 or ≥2 extranodal sites

Answer 11

R-CHOP x6 and CNS prophylaxis