28 - The Need for an Immune System Flashcards
define immune syst?
passive and active processes to protect body against harm
prophylactic and therapeutic function of IS?
Prophylactic
- prevent trouble developing
Therea
- sort problem out [cost of friendly fire]
why is IS decribed as policeman and discriminating?
police
- protect cells from foreign invaders
discrim
- between self cells and non self
what are the 3 systems of the immune system?
intrinic - prevent prob develop [barrier]
innate - recognise nonself NON-SPEC
adaptive - recognise nonself SPEC
where are immune cells made and then stored?
made in bonen marrow
t cells specialise in Thymus
store in spleen
3 factors immunity depends on?
correct no of cells [problem: neuropaenia/lymp]
able to travel to correct site? [poor vascularisation]
cells have appropriate molecules to kill [tubercloid]
how does the immune system kill by either being
- contact dependent
- soluble factors?
contact dep
- engulf
- communicate to co-ordinate response
sol fac
- immune cells prod sol factors to kill directly
- mols can regulate IS
what produces antibodies?
b-plasma cells
how do antibodies work by
- neutralization
- opsonization
- complement activation
N
-neutralise bacteria bind to it
O
- label pathogen to macrophages
C
- kills straight