264 Exam 2 Flashcards
What are the indications for medications for maintaining gas exchange?
1) Maintaining patency of respiratory tract.
2) ensure effective gas exchange between blood and tissues.
What do bronchodilators do?
Help to control and prevent symptoms.
What are some SABAs?
Salbutamol, Terbutaline
What are some LABAs?
Eformoterol, Indacaterol, Salmeterol, Vilanterol
What are some Sympathomimetic agents?
Adrenaline, Ephedrine
What are some antimuscarinic agents?
Aclidinium,, Glycopyrronium, Ipatropium, Tiotroipium
What are some methylxanthines?
Aminophylline, Theophylline
What are some topical (inhaled) corticosteroids?
Beclomethasone, Budesonide, Ciclesonide, Fluticasone
oxapramWhat are some systemic corticosteroides
Betamethasone, Dexamethasone, Hydrocortisone, Methylprednisolone, Prednisone
What are some respiratory stimulants?
Doxapram
What are some Asthma prophylactics
nedocromil sodium, sodium cromoglycate
Name a Leukotriene receptor antagonists
Montelukast
What are some surfactants?
Beractant, Poractant alfa
What are the 2 kinds of bronchdilators, and what are the 3 groups these are broken into?
SABAS and LABAS
3 groups - Beta2 agonists, antimuscarinic agents, methylxanthines
How do B2 agonists work
B2 agonists stimulate the B2 adrenergic receptors on bronchial smooth muscle
How do Antimuscarinic agents work
Block muscarinic cholinergic receptors in bronchial smooth muscle
How do Methylxanthines work?
Elevate the levels of intracellular messenger molecule cycle adenosine monophosphate modulating cellular activity.
What are some adverse effects fo B2 agonists?
Fine motor tremor
Palpitations
Peripheral vasodilation resulting in hypotension and headaches
What is the onset and duration of action for SABAs and LABAs?
SABAs = 15-20min and lasts 3-6 hours
LABAs = 1-30 min and lasts 12-24 hours
How do sympathomimetics work?
Produce bronchodilation by activating beta receptors and reducing oedema through pulmonary vasoconstriction
What do Antimuscarinic agents do?
Causes bronchodilation by blocking M3-muscarinic receptors associated with parasympathetic stimulation of the bronchial airways - results in reduction in visous mucous production related to obtstructive aiway diseases.
What are some adverse side effects of antimuscarinic agents?
Dry mouth
pupil dilation
urinary retention
glaucoma
How do methylxanthines work
Elevate the levels of intracellular messenger molecule cycle adenosine monophosphate modulating cellular activity
What are some adverse effects of methylxanthines?
Over stimulation of the nervous system
Insomnia
nervousness
epigastric distress
N and V
Tachycardia
siezures
venticular dysrhythmias