26 - IBD Flashcards
1
Q
IBD - EPI
A
18 - 24, then 70+
Big cities
America
Genetic (monozygotic twins 60%, children 10%, siblings 10%)
2
Q
Crohn’s Disease
A
Patchy inflammation Mouth to anus involvement Transmural inflammation Fistulas and strictures common Risk of cancer Extraintestinal mainfestations Higher risk for smokers Can have granulomas
3
Q
Ulcerative Colitis
A
Continuous inflammation Generally affects the colon Mucosal inflammation Fistulas and strictures seldom Risk of colorectal cancer Extraintestinal manifestations Lower risk for smokers Granulomas uncommon
4
Q
Ulcerative Colitis - Practical
A
Always bleeds
Only involves the colon
Protected by smoking
5
Q
Extraintestinal Mainfestations of IBD
A
Ocular disorders Aphthous stomatitis Ankylosing spondylitis Nephrolithiasis Sacroileitis Thromboembolic complications Skin disorders Peripheral arthritis Primary sclerosing cholangitis Hepatobiliary disorders
6
Q
Venn Diagram of IBD
A
Luminal Antigens
Genetic Susceptibility
Environmental Triggers
